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人体测量指标与膀胱过度活动症(OAB)之间的关联:一项基于2005 - 2018年美国国家健康与营养检查调查(NHANES)的横断面研究。

The Association Between Anthropometric Indices and Overactive Bladder (OAB): A Cross-Sectional Study From the NHANES 2005-2018.

作者信息

Zhong Meiru, Wang Zhou

机构信息

Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shangdong, China.

School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China.

出版信息

Neurourol Urodyn. 2025 Feb;44(2):345-359. doi: 10.1002/nau.25653. Epub 2024 Dec 29.

Abstract

BACKGROUND

The association between different anthropometric indices, including body mass index (BMI), a body shape index (ABSI), lipid accumulation product (LAP), visceral adiposity index (VAI), waist circumference-triglyceride index (WTI), weight-adjusted waist index (WWI), body roundness index (BRI) and the prevalence of overactive bladder (OAB) is unclear. This investigation aims to explore the association among different anthropometric indices and overactive bladder as well as confounding variables.

METHODS

Data were obtained from the USA National Health and Nutrition Examination Survey (NHANES) data set between 2005 and 2018, and 15231 participants were included in the study. Multivariable logistic regression was used to investigate the correlation among anthropometric indices mentioned in our study and overactive bladder. Subgroup analyses, smooth curve fitting and area under curve (AUC curve) were also performed.

RESULTS

There was a positive correlation between BMI, LAP, WTI, WWI, BRI and overactive bladder. The results were significant even after taking into account every covariate (p < 0.05). Fitting smooth curves demonstrated that when anthropometric indices were used as a predictor to predict the occurrence of OAB, the probability of female patients suffering from OAB was higher than that of male patients. Additionally, WWI had better predictive power (AUC = 0.6780) and VAI had the worst predictive power (AUC = 0.5558).

CONCLUSION

Our results suggest a substantial positive relationship between some of the anthropometric indices, including BMI, LAP, WTI, WWI, BRI, and overactive bladder.

摘要

背景

不同人体测量指标之间的关联,包括体重指数(BMI)、体型指数(ABSI)、脂质蓄积产物(LAP)、内脏脂肪指数(VAI)、腰围-甘油三酯指数(WTI)、体重校正腰围指数(WWI)、身体圆润度指数(BRI)与膀胱过度活动症(OAB)患病率之间的关系尚不清楚。本研究旨在探讨不同人体测量指标与膀胱过度活动症以及混杂变量之间的关联。

方法

数据来源于2005年至2018年美国国家健康与营养检查调查(NHANES)数据集,共纳入15231名参与者。采用多变量逻辑回归研究本研究中提到的人体测量指标与膀胱过度活动症之间的相关性。还进行了亚组分析、平滑曲线拟合和曲线下面积(AUC曲线)分析。

结果

BMI、LAP、WTI、WWI、BRI与膀胱过度活动症之间存在正相关。即使考虑了所有协变量,结果仍具有显著性(p < 0.05)。拟合平滑曲线表明,当将人体测量指标用作预测膀胱过度活动症发生的指标时,女性患者患膀胱过度活动症的概率高于男性患者。此外,WWI具有更好的预测能力(AUC = 0.6780),而VAI的预测能力最差(AUC = 0.5558)。

结论

我们的研究结果表明,包括BMI、LAP、WTI、WWI、BRI在内的一些人体测量指标与膀胱过度活动症之间存在显著的正相关关系。

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