Hui Zeng, Zewu Zhu, Yang Li, Yu Cui
Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Front Nutr. 2024 Sep 4;11:1423148. doi: 10.3389/fnut.2024.1423148. eCollection 2024.
The weight-adjusted waist index (WWI) is a novel obesity indicator that appears to outperform the body mass index (BMI) and waist circumference (WC) in assessing both overweight and obesity. Studies have demonstrated the relationship between obesity and overactive bladder (OAB). The purpose of this study is to examine the correlation between WWI and OAB.
This research utilizes data from the National Health and Nutrition Examination Survey (NHANES) collected between 2009 and 2018. Each participant's WWI was calculated as their WC in centimeters by the square root of weight in kilograms. The Overactive Bladder Symptom Score (OABSS) questionnaire is used to determine whether a participant has OAB. Multivariate logistic regression and generalized additive model analysis were employed to investigate the relationship between WWI and OAB. We used smoothing curve fitting to explore non-linear relationships. Additionally, subgroup analysis and interaction tests are conducted.
In this cross-sectional study involving 35,950 subjects, we found that individuals with a higher WWI have a higher risk of OAB (OR = 1.41, 95% CI: 1.02-1.74). Subgroup analysis and interaction testing showed that the relationship between WWI and OAB is consistent across various population characteristics. Smoothing curve fitting reveals a positive non-linear relationship between WWI and OAB. Furthermore, the association between WWI and OAB is stronger than that of other obesity-related indicators.
Weight-adjusted waist index may be able to predict the incidence of OAB and that WWI-based obesity management may help to reduce the risk of OAB.
体重调整腰围指数（WWI）是一种新型肥胖指标，在评估超重和肥胖方面似乎优于体重指数（BMI）和腰围（WC）。研究已经证明了肥胖与膀胱过度活动症（OAB）之间的关系。本研究的目的是探讨WWI与OAB之间的相关性。
本研究利用了2009年至2018年期间收集的美国国家健康与营养检查调查（NHANES）的数据。每个参与者的WWI通过其腰围（厘米）除以体重（千克）的平方根来计算。使用膀胱过度活动症症状评分（OABSS）问卷来确定参与者是否患有OAB。采用多变量逻辑回归和广义相加模型分析来研究WWI与OAB之间的关系。我们使用平滑曲线拟合来探索非线性关系。此外，还进行了亚组分析和交互作用检验。
在这项涉及35950名受试者的横断面研究中，我们发现WWI较高的个体患OAB的风险更高（OR = 1.41，95%CI：1.02 - 1.74）。亚组分析和交互作用检验表明，WWI与OAB之间的关系在各种人群特征中是一致的。平滑曲线拟合显示WWI与OAB之间存在正的非线性关系。此外，WWI与OAB之间的关联比其他肥胖相关指标更强。
体重调整腰围指数可能能够预测OAB的发生率，基于WWI的肥胖管理可能有助于降低OAB的风险。
