Tsamesidis Ioannis, Pappa Anastasia, Charisis Aggelos, Prentza Zoi, Theocharis Konstantinos, Patsias Apostolos, Foukas Dimitrios, Chatzidoukas Christos, Kalogianni Eleni P
Department of Food Science and Technology, Sindos Campus, International Hellenic University, 57400, Thessaloniki, Greece.
Agricultural Poultry Cooperation of Ioannina "PINDOS", 45500, Rodotopi, Ioannina, Greece.
Sci Rep. 2024 Dec 30;14(1):31588. doi: 10.1038/s41598-024-76998-3.
Microalgae, have emerged as a potentially promising feed additive option due to their beneficial nutritional profile rich in bioactive compounds. The present study examines the incorporation of Chlorella sorokiniana (at 0.1% and 1%) into chicken feed compared to control feed and its effect on growth and health parameters of poultry grown at pilot plant scale. Growth performance parameters (weight, feed conversion ratio (FCR), mortality, European Production Efficiency Index (EPEF)) and the immune system response are examined. In addition, it examines well-being gut health and nutrient absorption related variables via macroscopical and histological analysis. Finally, red blood cell (RBC) morphology and oxidative stress parameters (reactive oxygens species (ROS) and malondialdehyde level) in the whole blood as well as the lipid profile of the adipose tissue are determined. Addition of Chlorella sorokiniana at 0.1% resulted improved growth performance parameters whereas the ROS levels were significantly decreased indicating reduced oxidative stress. Finally, the results of histological analyses of the intestine on parameters related to nutrient absorption correlated with the results on growth performance. On the other hand, addition Chlorella sorokiniana at 1% did not affect significantly the growth performance parameters, resulted in increased footpad dermatitis, increased oxidative stress and alterations in RBC.
微藻因其富含生物活性化合物的有益营养成分而成为一种颇具潜力的饲料添加剂选择。本研究考察了将索氏小球藻（添加量为0.1%和1%）添加到鸡饲料中与对照饲料相比，对中试规模养殖家禽的生长和健康参数的影响。研究了生长性能参数（体重、饲料转化率（FCR）、死亡率、欧洲生产效率指数（EPEF））和免疫系统反应。此外，还通过宏观和组织学分析研究了肠道健康和营养吸收相关变量。最后，测定了全血中的红细胞（RBC）形态和氧化应激参数（活性氧（ROS）和丙二醛水平）以及脂肪组织的脂质谱。添加0.1%的索氏小球藻可改善生长性能参数，而ROS水平显著降低，表明氧化应激减轻。最后；肠道组织学分析中与营养吸收相关参数的结果与生长性能结果相关。另一方面，添加1%的索氏小球藻对生长性能参数没有显著影响，导致脚垫皮炎增加、氧化应激增加和红细胞改变。
