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柔性可导航输尿管接入鞘与传统输尿管接入鞘在小儿逆行性肾内手术中的比较:单中心倾向匹配分析

Comparison of flexible and navigable suction ureteral access sheath with conventional ureteral access sheath for pediatric retrograde intrarenal surgery: a single-center propensity-matched analysis.

作者信息

Turedi Bilge, Sezer Ali

机构信息

Pediatric Urology Clinic, Konya City Hospital, Karatay, Konya, 42020, Turkey.

出版信息

Urolithiasis. 2024 Dec 31;53(1):17. doi: 10.1007/s00240-024-01686-w.

Abstract

The flexible and navigable suction ureteral access sheath (FANS-UAS) has increasingly been recognized as a potential game changer for retrograde intrarenal surgery (RIRS). While this innovative technology has demonstrated promising results in adult populations, there is a notable lack of evidence regarding its application in pediatric cases, particularly in comparison to conventional ureteral access sheaths (CUAS). This study aimed to perform a comparative analysis of pediatric kidney stone cases treated with RIRS using FANS-UAS and CUAS. We conducted a retrospective matched pair analysis, matching patients based on preoperative age, stone location, and stone size. After matching, data from 46 patients (23 in each group) were analyzed. The groups were comparable in terms of age, hydronephrosis degree, location and size of the stone (p = 0.543, p = 0.807, p = 0.840, and p = 0.577, respectively). Operation times were shorter in the FANS-UAS group (CUAS: 67.9 ± 21.0 min, FANS-UAS: 50.4 ± 21.1 min, p = 0.007). The initial stone-free rate (SFR) was 65.2% in the CUAS group and 91.3% in the FANS-UAS group, with a statistically significant difference (p = 0.032). However, no significant difference was found regarding the final SFR (p = 0.295). The number and duration of DJ-stents, were significantly higher in the CUAS group (p = 0.006 for both). The FANS-UAS group had a significantly fewer anesthesia sessions (p = 0.001). There were no significant differences in complication rates (p = 0.303). Our findings suggest that FANS-UAS offers significant advantages over CUAS in pediatric RIRS, including higher initial success rates, shorter operation times, reduced anesthesia requirements, and fewer treatment sessions, with comparable safety profiles.

摘要

可弯曲导航式输尿管吸引鞘(FANS-UAS)越来越被认为是逆行性肾内手术(RIRS)的一个潜在变革者。虽然这项创新技术在成人患者中已显示出有前景的结果,但关于其在儿科病例中的应用,特别是与传统输尿管鞘(CUAS)相比,明显缺乏证据。本研究旨在对使用FANS-UAS和CUAS进行RIRS治疗的小儿肾结石病例进行对比分析。我们进行了一项回顾性配对分析,根据术前年龄、结石位置和结石大小对患者进行配对。配对后,分析了46例患者(每组23例)的数据。两组在年龄、肾积水程度、结石位置和大小方面具有可比性(分别为p = 0.543、p = 0.807、p = 0.840和p = 0.577)。FANS-UAS组的手术时间更短(CUAS组:67.9±21.0分钟,FANS-UAS组:50.4±21.1分钟,p = 0.007)。CUAS组的初始无石率(SFR)为65.2%,FANS-UAS组为91.3%,差异有统计学意义(p = 0.032)。然而,最终SFR方面未发现显著差异(p = 0.295)。CUAS组的DJ支架数量和留置时间显著更高(两者p均 = 0.006)。FANS-UAS组的麻醉次数显著更少(p = 0.001)。并发症发生率无显著差异(p = 0.303)。我们的研究结果表明,在小儿RIRS中,FANS-UAS相对于CUAS具有显著优势,包括更高的初始成功率、更短的手术时间所需、减少麻醉需求以及更少的治疗次数,且安全性相当。

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