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可弯曲和可操控的输尿管吸引鞘(FANS-UAS)是否是儿童逆行性肾内手术的下一个最佳发展?一项前瞻性多中心研究的结果。

Is flexible and navigable suction ureteral access sheath (FANS-UAS) the next best development for retrograde intrarenal surgery in children? Results of a prospective multicentre study.

机构信息

Department of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.

Department of Urology, Fundació Puigvert, Carrer de Cartagena, 340-350, Barcelona, 08025, Spain.

出版信息

World J Urol. 2024 Nov 6;42(1):627. doi: 10.1007/s00345-024-05337-y.

DOI:10.1007/s00345-024-05337-y
PMID:39503864
Abstract

PURPOSE

To assess retrograde intrarenal surgery (RIRS) outcomes in children using ClearPetra, a flexible and navigable suction ureteral access sheath (FANS-UAS).

METHODS

Children with kidney stone(s) only undergoing RIRS in 8 centers were prospectively included (September 2023-May 2024).

EXCLUSION CRITERIA

ureteral stone, bilateral procedures, anomalous kidneys, surgery for residual fragments. Lithotripsy was performed using either a Holmium or Thulium fiber laser. Postoperative pain was assessed within 24 h using a 10-point visual analogue score. The use of FANS-UAS was graded by surgeons after each case using a 5-point likert scale. Low-dose non-contrast CT scan was performed before and within 30 days of RIRS to assess residual fragments (RFs). Stone-free status was defined as no RF or single RF up to 2 mm.

RESULTS

50 children were included. 66% were male. Mean age was 6.6 (± 3.38) years. 88% stones were < 2 cm. one-third of the patients had a stone volume > 1500mm. 10-12 Fr FANS-UAS was used in 98% of the procedure. The mean operative time was 46.02 (± 20.72) minutes. 2 patients had Traxer grade1 distal ureter and 2 forniceal injuries on sheath placement. Mean pain score was 2.18 (± 1.34). Mean likert scale was 1.16 (± 0.47) for ease of suction, 1.24 (± 0.52) for manipulation, 1.02 (± 0.32) for visibility. 4 patients had post-operative fever lasting less than 24 h. No sepsis occurred. Stone-free rate was 100%.

CONCLUSIONS

Our study shows that the use of FANS-UAS in paediatric RIRS is feasible and safe with a low rate of complications and excellent stone-free rate.

摘要

目的

评估使用可弯曲、可导航的抽吸输尿管接入鞘(FANS-UAS)行逆行肾内手术(RIRS)治疗儿童肾结石的效果。

方法

8 家中心前瞻性纳入仅接受 RIRS 的肾结石儿童患者(2023 年 9 月至 2024 年 5 月)。

排除标准

输尿管结石、双侧手术、异常肾脏、残石手术。碎石采用钬激光或铥光纤激光。术后 24 小时内采用 10 分制视觉模拟评分评估术后疼痛。每位患者手术后,术者采用 5 分 Likert 量表对 FANS-UAS 的使用进行分级。RIRS 术前和术后 30 天内行低剂量非增强 CT 扫描评估残石(RFs)。无 RF 或单个最大直径不超过 2mm 的 RF 定义为结石清除。

结果

共纳入 50 例患儿,66%为男性,平均年龄 6.6(±3.38)岁,88%的结石<2cm,1/3 的患者结石体积>1500mm³。98%的患者使用 10-12Fr FANS-UAS。平均手术时间为 46.02(±20.72)分钟,2 例患者在鞘管置入时出现 TraxerⅠ级远端输尿管损伤,2 例出现穹窿损伤。平均疼痛评分为 2.18(±1.34),Likert 量表评分中,抽吸的舒适度评分为 1.16(±0.47),操作的便利性评分为 1.24(±0.52),可视性评分为 1.02(±0.32)。4 例患者术后发热持续时间<24 小时,无脓毒症发生。结石清除率为 100%。

结论

本研究表明,在儿科 RIRS 中使用 FANS-UAS 是可行且安全的,并发症发生率低,结石清除率高。

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Eur Urol Focus. 2024 Jan;10(1):154-168. doi: 10.1016/j.euf.2023.06.010. Epub 2023 Jul 11.
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