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Klotho shapes kidney complications during chemotherapy in hematological patients.

作者信息

Simonini Marco, Mastaglio Sara, Citterio Lorena, Zagato Laura, El Boustani Maguie, Ciceri Fabio, Lanzani Chiara

机构信息

Nephrology and Dialysis Unit, Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy.

Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

出版信息

J Nephrol. 2024 Dec 30. doi: 10.1007/s40620-024-02151-y.

DOI:10.1007/s40620-024-02151-y
PMID:39738979
Abstract
摘要

相似文献

1
Klotho shapes kidney complications during chemotherapy in hematological patients.在血液学患者化疗期间，α-klotho蛋白影响肾脏并发症。
J Nephrol. 2024 Dec 30. doi: 10.1007/s40620-024-02151-y.
2
Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study.可溶性平均α-klotho水平作为急性肾损伤预后标志物的90天随访研究。
Biomark Med. 2025 Apr;19(7):243-250. doi: 10.1080/17520363.2025.2481018. Epub 2025 Mar 22.
3
Association of serum Klotho and fibroblast growth factor-23 levels with vascular calcification severity in patients with chronic kidney disease: an observational cohort study.慢性肾病患者血清α-klotho和成纤维细胞生长因子-23水平与血管钙化严重程度的关联：一项观察性队列研究
Int Urol Nephrol. 2025 Apr 1. doi: 10.1007/s11255-025-04475-5.
4
Pathophysiologic Implications and Therapeutic Approach of Klotho in Chronic Kidney Disease: A Systematic Review.Klotho 在慢性肾脏病中的病理生理意义及治疗方法：系统评价。
Lab Invest. 2023 Jul;103(7):100178. doi: 10.1016/j.labinv.2023.100178. Epub 2023 May 18.
5
Expression of FGF23 and α-KLOTHO in Normal Human Kidney Development and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).FGF23和α-klotho在正常人类肾脏发育及肾和尿路先天性异常（CAKUT）中的表达
Biomolecules. 2025 Jun 4;15(6):811. doi: 10.3390/biom15060811.
6
Klotho modulation by tempol: a potential therapeutic axis in sepsis.Tempol对Klotho的调节作用：脓毒症的潜在治疗靶点。
BMC Cardiovasc Disord. 2025 Jul 5;25(1):492. doi: 10.1186/s12872-025-04738-0.
7
Serum Klotho protein level in patients with thyroid dysfunction.甲状腺功能障碍患者的血清klotho蛋白水平。
Ir J Med Sci. 2025 Mar 31. doi: 10.1007/s11845-025-03937-0.
8
Clinical value of serum Klotho protein in patients with acute traumatic brain injury complicated by acute kidney injury.血清Klotho蛋白在急性创伤性脑损伤合并急性肾损伤患者中的临床价值。
Sci Rep. 2025 Jul 1;15(1):20468. doi: 10.1038/s41598-025-05201-y.
9
Bidirectional upregulation of Klotho by triiodothyronine and baicalein: mitigating chronic kidney disease and associated complications in aged BALB/c mice.三碘甲状腺原氨酸和黄芩苷对Klotho的双向上调作用：减轻老年BALB/c小鼠的慢性肾病及相关并发症
Biogerontology. 2025 May 26;26(3):114. doi: 10.1007/s10522-025-10257-4.
10
Triiodothyronine enhances various forms of kidney-specific Klotho protein and suppresses the Wnt/β-catenin pathway: Insights from in-vitro, in-vivo and in-silico investigations.三碘甲状腺原氨酸增强各种形式的肾脏特异性 Klotho 蛋白并抑制 Wnt/β-连环蛋白通路：来自体外、体内和计算机模拟研究的见解。
Cell Signal. 2024 Aug;120:111214. doi: 10.1016/j.cellsig.2024.111214. Epub 2024 May 9.

本文引用的文献

1
Recombinant Klotho alleviates vancomycin-induced acute kidney injury by upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis.重组 Klotho 通过 JAK2/STAT3/GPx3 轴上调抗氧化能力缓解万古霉素诱导的急性肾损伤。
Toxicology. 2023 Nov;499:153657. doi: 10.1016/j.tox.2023.153657. Epub 2023 Oct 25.
2
Incidence and Risk Factors for Acute Kidney Injury after Allogeneic Stem Cell Transplantation: A Prospective Study.异基因干细胞移植后急性肾损伤的发病率及危险因素：一项前瞻性研究
Biomedicines. 2022 Jan 25;10(2):262. doi: 10.3390/biomedicines10020262.
3
Acute Kidney Injury in the Modern Era of Allogeneic Hematopoietic Stem Cell Transplantation.
异基因造血干细胞移植时代的急性肾损伤。
Clin J Am Soc Nephrol. 2021 Sep;16(9):1318-1327. doi: 10.2215/CJN.19801220. Epub 2021 Jun 16.
4
Fibroblast growth factor 23: are we ready to use it in clinical practice?成纤维细胞生长因子 23：我们是否已准备好在临床实践中使用它？
J Nephrol. 2020 Jun;33(3):509-527. doi: 10.1007/s40620-020-00715-2. Epub 2020 Mar 4.
5
Klotho Gene in Human Salt-Sensitive Hypertension.Klotho 基因与人类盐敏感性高血压
Clin J Am Soc Nephrol. 2020 Mar 6;15(3):375-383. doi: 10.2215/CJN.08620719. Epub 2020 Jan 28.
6
Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.成年患者急性淋巴细胞白血病：ESMO诊断、治疗及随访临床实践指南
Ann Oncol. 2016 Sep;27(suppl 5):v69-v82. doi: 10.1093/annonc/mdw025. Epub 2016 Apr 7.
7
KDIGO clinical practice guidelines for acute kidney injury.改善全球肾脏病预后组织（KDIGO）急性肾损伤临床实践指南
Nephron Clin Pract. 2012;120(4):c179-84. doi: 10.1159/000339789. Epub 2012 Aug 7.
8
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective.Klotho 缺乏是肾缺血再灌注损伤的早期生物标志物，其替代物具有保护作用。
Kidney Int. 2010 Dec;78(12):1240-51. doi: 10.1038/ki.2010.328. Epub 2010 Sep 22.