Riviere Y, Ahmed R, Southern P J, Buchmeier M J, Dutko F J, Oldstone M B
J Virol. 1985 Mar;53(3):966-8. doi: 10.1128/JVI.53.3.966-968.1985.
The lymphocytic choriomeningitis virus (LCMV) genome consists of a large RNA segment and a small RNA segment. The three major structural proteins of this virus are an internal nucleoprotein and two surface glycoproteins. Intertypic reassortants between the Armstrong and WE strains of LCMV were made to map proteins encoded by the LCMV genome segments. Using monoclonal antibodies specific for the nucleoprotein and the glycoproteins of WE and Armstrong, we showed that the small RNA segment of LCMV codes for the three major structural polypeptides.
淋巴细胞性脉络丛脑膜炎病毒(LCMV)基因组由一个大的RNA片段和一个小的RNA片段组成。该病毒的三种主要结构蛋白是一种内部核蛋白和两种表面糖蛋白。构建了LCMV阿姆斯特朗株和WE株之间的型间重配体,以定位由LCMV基因组片段编码的蛋白质。使用针对WE株和阿姆斯特朗株的核蛋白及糖蛋白的单克隆抗体,我们发现LCMV的小RNA片段编码这三种主要结构多肽。