Cheng Dai, Wenying Ding, Jizheng Huang, Wei Sun, Liang Li, Guolei Han, Hao Yang
Department of Intensive Care Medicine, No.2 People's Hospital of Fuyang City, Fuyang, China.
Department of Hospital Infection Management, No.2 People's Hospital of Fuyang City, Fuyang, China.
PLoS One. 2024 Dec 31;19(12):e0316196. doi: 10.1371/journal.pone.0316196. eCollection 2024.
This study aimed to analyze the predictive value of the systemic immune inflammation index (SII) for the severity of disease in tetanus patients.
Clinical data of 34 tetanus patients admitted to the Second People's Hospital of Fuyang from January 1, 2019 to December 31, 2022 were analyzed. Based on whether patients received intensive care unit (ICU) treatment after admission, the patients were divided into ICU and non-ICU groups. The diagnostic value of SII for the severity of tetanus was assessed.
Among the 34 patients, 18 (52.90%) were classified into the ICU group, and 16 (47.10%) into the non-ICU group. There were statistically significant differences in white blood cell count, platelet count, neutrophil count, and SII between the two groups (P<0.05). Logistic regression analysis revealed that SII was a risk factor for tetanus patients requiring ICU treatment. The area under the curve (AUC) for SII predicting ICU treatment in tetanus patients was 0.896 (95% CI 0.790-1.000, P<0.001).
The SII can serve as an objective predictive indicator for tetanus patients requiring ICU treatment.
本研究旨在分析全身免疫炎症指数（SII）对破伤风患者疾病严重程度的预测价值。
分析2019年1月1日至2022年12月31日期间阜阳市第二人民医院收治的34例破伤风患者的临床资料。根据患者入院后是否接受重症监护病房（ICU）治疗，将患者分为ICU组和非ICU组。评估SII对破伤风严重程度的诊断价值。
34例患者中，18例（52.90%）被归入ICU组，16例（47.10%）被归入非ICU组。两组患者的白细胞计数、血小板计数、中性粒细胞计数和SII存在统计学显著差异（P<0.05）。Logistic回归分析显示，SII是破伤风患者需要ICU治疗的危险因素。SII预测破伤风患者ICU治疗的曲线下面积（AUC）为0.896（95%CI 0.790-1.000，P<0.001）。
SII可作为破伤风患者需要ICU治疗的客观预测指标。
