Nydegger U, Farquet J J, Zubler R, Lambert P H, Miescher P A
Med Microbiol Immunol. 1979;167(4):261-8. doi: 10.1007/BF02120811.
Complement analyses performed on serially collected plasma samples from 10 patients during acute infectious pneumonia or bronchopneumonia showed normal or increased values for hemolytic activity and Clq, C4, C3, and factor B levels. However, the levels of C3 breakdown products (C3d) were significantly (greater than 2 SD) increased in six patients during the first three days of observation, suggesting that hypercatabolism of complement components may occur during the acute phase of infectious pneumonia concomitant with a hypersynthesis of some complement components. Evidence of circulating immune complexes was obtained only in two patients with the 125I-Clq Binding Test.
对10例急性感染性肺炎或支气管肺炎患者连续采集的血浆样本进行补体分析，结果显示溶血活性以及Clq、C4、C3和B因子水平正常或升高。然而，在观察的前三天，6例患者的C3裂解产物（C3d）水平显著升高（大于2个标准差），这表明在感染性肺炎急性期可能会发生补体成分的高分解代谢，同时伴有一些补体成分的超合成。仅在2例患者中通过125I-Clq结合试验获得了循环免疫复合物的证据。
