Cai Wei, Deng Yuhang, Xu Pan, Xue Jianjiang
Department of Laboratory Medicine, University Town Hospital of Chongqing Medical University, No. 55, Middle Road University, Chongqing, 410331, China.
Virol J. 2024 Dec 31;21(1):340. doi: 10.1186/s12985-024-02594-6.
To analyze the molecular epidemiological characteristics of influenza viruses in influenza-like cases in Chongqing Hi-Tech Zone, China, to provide data support and a scientific basis for optimizing influenza prevention and control strategies in the region.
A retrospective analysis was conducted on the molecular epidemiological characteristics of influenza viruses in influenza-like cases at a hospital in Chongqing Hi-Tech Zone from 2021 to 2024. Colloidal gold detection of viral antibodies, fluorescent PCR detection of nucleic acids, and gene sequencing were used to identify the different subtypes.
Among 39,986 ILI specimens tested using the immunocolloid gold method, 6,616 influenza viruses were detected, with a detection rate of 16.54%. Infections included 4,464 influenza A viruses (67.50%), 2,033 influenza B viruses (30.73%), and 119 co-infections of influenza A and B viruses (1.77%).In this region, H3N2 was the predominant subtype of influenza A, and Victoria was the main subtype of influenza B.
Influenza epidemics in the winter and spring seasons in Chongqing Hi-Tech Zone were predominantly caused by influenza A, with influenza B also circulating. Influenza A strains were mainly H3N2, while influenza B strains were primarily Victoria.
分析中国重庆高新区流感样病例中流感病毒的分子流行病学特征，为优化该地区流感防控策略提供数据支持和科学依据。
对重庆高新区某医院2021年至2024年流感样病例中流感病毒的分子流行病学特征进行回顾性分析。采用胶体金法检测病毒抗体、荧光PCR法检测核酸以及基因测序来鉴定不同亚型。
采用免疫胶体金法检测的39986份流感样病例标本中，共检测出6616份流感病毒，检出率为16.54%。其中甲型流感病毒感染4464例（67.50%），乙型流感病毒感染2033例（30.73%），甲乙型流感病毒混合感染119例（1.77%）。该地区甲型流感以H3N2亚型为主，乙型流感以Victoria亚型为主。
重庆高新区冬春季节流感流行以甲型流感为主，乙型流感也有流行。甲型流感毒株主要为H3N2，乙型流感毒株主要为Victoria。
