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多功能荧光磁性铂纳米簇的合成与表征

Synthesis and Characterization of Multifunctional Fluorescent-Magnetic Platinum Nanoclusters.

作者信息

Tanaka Shin-Ichi, Yamagami Kohei, Sato Kazuhisa, Yasuda Hidehiro, Niioka Hirohiko, Wadati Hiroki

机构信息

National Institute of Technology, Kure College, 2-2-11 Agaminami, Kure, Hiroshima 737-8506, Japan.

Japan Synchrotron Radiation Research Institute (JASRI), 1-1-1 Kouto, Sayo-gun, Sayo-cho, Hyogo 679-5198, Japan.

出版信息

ACS Omega. 2024 Dec 13;9(51):50349-50356. doi: 10.1021/acsomega.4c06765. eCollection 2024 Dec 24.

DOI:10.1021/acsomega.4c06765
PMID:39741844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11683621/
Abstract

There is great interest in the development of new multifunctional fluorescent-magnetic nanomaterials for use as multimodal diagnostic imaging probes and site-specific drug delivery tools. Metal nanoclusters (NCs) have been reported to possess either fluorescent or magnetic properties, but not both. In this paper, we report the synthesis and characterization of multifunctional fluorescent-magnetic Pt NCs. Our synthesized NCs (0.8 ± 0.2 nm in diameter) exhibit both bright red fluorescence (excitation: 535 nm, emission: 620 nm) and ferromagnetic behavior with hysteresis, which represents a noteworthy and significant advance in the development of Pt NCs. Our findings suggest the potential of our NCs to be applied in multimodal fluorescent-magnetic nanomaterials for biomedical applications.

摘要

人们对开发新型多功能荧光磁性纳米材料作为多模态诊断成像探针和位点特异性药物递送工具有着浓厚的兴趣。据报道，金属纳米团簇（NCs）具有荧光或磁性特性，但并非兼具两者。在本文中，我们报告了多功能荧光磁性铂纳米团簇的合成与表征。我们合成的纳米团簇（直径为0.8±0.2纳米）既表现出亮红色荧光（激发波长：535纳米，发射波长：620纳米），又具有带磁滞的铁磁行为，这代表了铂纳米团簇开发方面一项值得注意的重大进展。我们的研究结果表明，我们的纳米团簇有潜力应用于生物医学应用的多模态荧光磁性纳米材料中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/45439cffd8da/ao4c06765_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/21ee96f225fe/ao4c06765_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/cb1261138512/ao4c06765_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/a64d6b3b8dff/ao4c06765_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/3baceb075d43/ao4c06765_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/45439cffd8da/ao4c06765_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/21ee96f225fe/ao4c06765_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/cb1261138512/ao4c06765_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/a64d6b3b8dff/ao4c06765_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/3baceb075d43/ao4c06765_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ec/11683621/45439cffd8da/ao4c06765_0005.jpg

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