• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

生物气溶胶的非致癌健康风险评估

Non-carcinogenic health risks assessment of bioaerosols.

作者信息

Siddique Azhar, Rasool Kashif

机构信息

Qatar Environment and Energy Research Institue (QEERI), Hamad Bin Khalifa University, Doha, Qatar.

出版信息

MethodsX. 2024 Dec 9;14:103088. doi: 10.1016/j.mex.2024.103088. eCollection 2025 Jun.

DOI:10.1016/j.mex.2024.103088
PMID:39741892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11683212/
Abstract

Bioaerosols, pose potential health risks, yet quantitative assessments of non-carcinogenic risks from bioaerosol inhalation are limited. This study introduces a novel approach for assessing non-carcinogenic health risks using bioaerosol exposure data. The method employs the Average Daily Dose and Hazard Quotient (HQ) metrics, adapted from US Environmental Protection Agency guidelines, with the Reference Dose (RfD) based on thresholds from the National Institute of Occupational Safety and Health and the American Conference of Governmental Industrial Hygienists. This study utilizes a time-weighted approach, considering age-specific inhalation rates and body weights, to enhance the precision of lifetime exposure assessments. This methodology was applied to data collected over one year across multiple locations in Qatar, assessing seasonal and site-specific variations in risk. Results indicate generally low health risks, with HQ values below 1 for most sites and seasons. However, the study identified elevated HQ values at highly active sites during the dry summer, suggesting potential health concerns that need urgent attention. The proposed framework offers a replicable approach for evaluating bioaerosol-related health risks across diverse environments.•Novel adaptation of HQ-based risk assessment for bioaerosols in Qatar, incorporating a time-weighted approach.•Evaluation of seasonal and site-specific exposure dynamics.•Designed for replicability in different environmental conditions.

摘要

生物气溶胶会带来潜在的健康风险,然而,对吸入生物气溶胶所致非致癌风险的定量评估却很有限。本研究引入了一种利用生物气溶胶暴露数据评估非致癌健康风险的新方法。该方法采用了根据美国环境保护局指南改编的平均每日剂量和危害商数(HQ)指标,参考剂量(RfD)基于美国国家职业安全与健康研究所和美国政府工业卫生学家会议的阈值。本研究采用时间加权方法,考虑特定年龄的吸入率和体重,以提高终生暴露评估的精度。该方法应用于卡塔尔多个地点一年多来收集的数据,评估风险的季节性和特定地点差异。结果表明,总体健康风险较低,大多数地点和季节的HQ值低于1。然而,该研究发现,在干燥的夏季,高活动场所的HQ值升高,这表明存在需要紧急关注的潜在健康问题。所提出的框架为评估不同环境中与生物气溶胶相关的健康风险提供了一种可重复的方法。•在卡塔尔对基于HQ的生物气溶胶风险评估进行了新的改编,纳入了时间加权方法。•评估季节性和特定地点的暴露动态。•设计用于在不同环境条件下进行复制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/e31aec2de439/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/5003936c8657/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/7203a3142983/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/e31aec2de439/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/5003936c8657/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/7203a3142983/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ee/11683212/e31aec2de439/gr2.jpg

相似文献

1
Non-carcinogenic health risks assessment of bioaerosols.生物气溶胶的非致癌健康风险评估
MethodsX. 2024 Dec 9;14:103088. doi: 10.1016/j.mex.2024.103088. eCollection 2025 Jun.
2
Evaluation of Seasonal Variation on the Health Risks Using the Quantitative Microbial Risk Assessment Approach in a Wastewater Treatment Plant in Hamadan, Iran.利用定量微生物风险评估方法评估伊朗哈马丹市污水处理厂健康风险的季节性变化。
J Res Health Sci. 2023 Mar;23(1):e00576. doi: 10.34172/jrhs.2023.111.
3
Health risks of inhalation exposure to BTEX in a municipal wastewater treatment plant in Middle East city: Shiraz, Iran.在伊朗设拉子市的一家中东城市的市政污水处理厂,人们因吸入 BTEX 而面临的健康风险。
Environ Res. 2022 Mar;204(Pt B):112155. doi: 10.1016/j.envres.2021.112155. Epub 2021 Oct 1.
4
Sources, pathways, and relative risks of contaminants in surface water and groundwater: a perspective prepared for the Walkerton inquiry.地表水和地下水中污染物的来源、途径及相对风险:为沃克顿调查准备的一份报告
J Toxicol Environ Health A. 2002 Jan 11;65(1):1-142. doi: 10.1080/152873902753338572.
5
Comparative analysis of bioaerosol emissions: Seasonal dynamics and exposure risks in hospital vs. municipal wastewater treatment systems.生物气溶胶排放的比较分析:医院与市政污水处理系统的季节性动态和暴露风险。
Environ Pollut. 2024 Oct 15;359:124608. doi: 10.1016/j.envpol.2024.124608. Epub 2024 Jul 23.
6
Bioaerosol in a typical municipal wastewater treatment plant: concentration, size distribution, and health risk assessment.典型城市污水处理厂中的生物气溶胶:浓度、粒径分布及健康风险评估。
Water Sci Technol. 2020 Oct;82(8):1547-1559. doi: 10.2166/wst.2020.416.
7
[Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)].[氯化乙酰甲胆碱支气管激发试验标准技术规范(2023年)]
Zhonghua Jie He He Hu Xi Za Zhi. 2024 Feb 12;47(2):101-119. doi: 10.3760/cma.j.cn112147-20231019-00247.
8
Quantitative microbial risk assessment for occupational health of temporary entrants and staffs equipped with various grade PPE and exposed to microbial bioaerosols in two WWTPs.对配备不同等级个人防护装备(PPE)并暴露于两个污水处理厂微生物生物气溶胶的临时入境者和工作人员的职业健康进行定量微生物风险评估。
Int Arch Occup Environ Health. 2021 Aug;94(6):1327-1343. doi: 10.1007/s00420-021-01663-5. Epub 2021 Mar 15.
9
Evaluation of exposure-response relationships for health effects of microbial bioaerosols - A systematic review.微生物生物气溶胶对健康影响的暴露-反应关系评估——一项系统综述
Int J Hyg Environ Health. 2015 Oct;218(7):577-89. doi: 10.1016/j.ijheh.2015.07.004. Epub 2015 Jul 18.
10
Insight Study of Trace Elements in PM During Nine Years in Delhi, India: Seasonal Variation, Source Apportionment, and Health Risks Assessment.印度德里九年来 PM 中微量元素的深入研究:季节性变化、来源解析和健康风险评估。
Arch Environ Contam Toxicol. 2024 May;86(4):393-409. doi: 10.1007/s00244-024-01070-0. Epub 2024 May 28.

引用本文的文献

1
Self-activating air filtration device for aerosol control during luminal instruments drying in the sterile processing department.用于无菌处理部门腔内器械干燥过程中气溶胶控制的自激活空气过滤装置。
PLoS One. 2025 Sep 10;20(9):e0331485. doi: 10.1371/journal.pone.0331485. eCollection 2025.

本文引用的文献

1
Seasonal and spatial variations in concentration, diversity, and antibiotic resistance of ambient bioaerosols in an arid region.干旱地区环境生物气溶胶浓度、多样性和抗生素耐药性的季节性和空间变化。
Environ Res. 2024 Dec 1;262(Pt 2):119879. doi: 10.1016/j.envres.2024.119879. Epub 2024 Sep 5.
2
Characteristics of bioaerosol emissions from a municipal wastewater treatment plant: Health risk assessment and microbial composition.城市污水处理厂生物气溶胶排放特征:健康风险评估与微生物组成。
Sci Total Environ. 2024 Jul 15;934:173096. doi: 10.1016/j.scitotenv.2024.173096. Epub 2024 May 8.
3
Beyond the outdoors: indoor air quality guidelines and standards - challenges, inequalities, and the path forward.
Rev Environ Health. 2023 Dec 27;40(1):21-35. doi: 10.1515/reveh-2023-0150. Print 2025 Mar 26.
4
A manifesto for reproducible science.可重复科学宣言。
Nat Hum Behav. 2017 Jan 10;1(1):0021. doi: 10.1038/s41562-016-0021.
5
Quantitative microbial risk assessment for occupational health of temporary entrants and staffs equipped with various grade PPE and exposed to microbial bioaerosols in two WWTPs.对配备不同等级个人防护装备(PPE)并暴露于两个污水处理厂微生物生物气溶胶的临时入境者和工作人员的职业健康进行定量微生物风险评估。
Int Arch Occup Environ Health. 2021 Aug;94(6):1327-1343. doi: 10.1007/s00420-021-01663-5. Epub 2021 Mar 15.
6
Bioaerosol in a typical municipal wastewater treatment plant: concentration, size distribution, and health risk assessment.典型城市污水处理厂中的生物气溶胶:浓度、粒径分布及健康风险评估。
Water Sci Technol. 2020 Oct;82(8):1547-1559. doi: 10.2166/wst.2020.416.
7
Ambient bioaerosol distribution and associated health risks at a high traffic density junction at Dehradun city, India.印度德拉敦市交通密集路口周围环境生物气溶胶分布及相关健康风险。
Environ Monit Assess. 2020 Feb 22;192(3):196. doi: 10.1007/s10661-020-8158-9.
8
Influence of indoor factors in dwellings on the development of childhood asthma.住宅室内因素对儿童哮喘发病的影响。
Int J Hyg Environ Health. 2011 Jan;214(1):1-25. doi: 10.1016/j.ijheh.2010.08.009. Epub 2010 Sep 18.
9
Atmospheric movement of microorganisms in clouds of desert dust and implications for human health.沙漠尘土云中微生物的大气运动及其对人类健康的影响。
Clin Microbiol Rev. 2007 Jul;20(3):459-77, table of contents. doi: 10.1128/CMR.00039-06.
10
Air pollution and health.空气污染与健康。
Lancet. 2002 Oct 19;360(9341):1233-42. doi: 10.1016/S0140-6736(02)11274-8.