小鼠SM品系中肌营养不良（dy）基因座处的一个新突变体。
A new mutant at the Dystrophia muscularis (dy) locus in the SM strain of mice.
作者信息
Hayakawa J, Tsuji S
出版信息
Lab Anim. 1985 Jan;19(1):1-2. doi: 10.1258/002367785780890677.
PMID:3974191
Abstract
Muscular dystrophy was found in the SM strain of mice. This defect was shown to be caused by a single autosomal recessive gene allelic with the genes at the dy locus. The dystrophic SM mice may provide a useful animal model for human muscular dystrophy, because SM strain has been selected for small body size and carries rare alleles at several loci.
摘要
在小鼠的SM品系中发现了肌肉萎缩症。已证明这种缺陷是由一个常染色体隐性基因引起的，该基因与dy位点的基因等位。患有肌肉萎缩症的SM小鼠可能为人类肌肉萎缩症提供一个有用的动物模型，因为SM品系已因体型小而被选育，并且在几个位点携带稀有等位基因。
Zotero 插件