Policy brief: Improving national vaccination decision-making through data.

Life course immunisation looks at the broad value of vaccination across multiple generations, calling for more data power, collaboration, and multi-disciplinary work. Rapid strides in artificial intelligence, such as machine learning and natural language processing, can enhance data analysis, conceptual modelling, and real-time surveillance. The GRADE process is a valuable tool in informing public health decisions. It must be enhanced by real-world data which can span and capture immediate needs in diverse populations and vaccination administration scenarios. Analysis of data from multiple study designs is required to understand the nuances of health behaviors and interventions, address gaps, and mitigate the risk of bias or confounding presented by any single data collection methodology. Secure and responsible health data sharing across European countries can contribute to a deeper understanding of vaccines.