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病例报告:Dieulafoy病变作为大量胃肠道出血的罕见原因。

Case report: Dieulafoy's lesion as a rare cause of massive gastrointestinal hemorrhage.

作者信息

Touati Med Dheker, Bouzid Ahmed, Hajji Rania, Ben Othmane Med Raouf, Belhadj Anis, Chebbi Faouzi

机构信息

General Surgery Department, Mahmoud El Matri Hospital, V59M+628, Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, R534+F9H, Rue de la Faculté de Médecine, Tunis, Tunisia.

General Surgery Department, Mahmoud El Matri Hospital, V59M+628, Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, R534+F9H, Rue de la Faculté de Médecine, Tunis, Tunisia.

出版信息

Int J Surg Case Rep. 2025 Jan;126:110810. doi: 10.1016/j.ijscr.2024.110810. Epub 2024 Dec 30.

Abstract

INTRODUCTION AND IMPORTANCE

Dieulafoy's lesion is a rare but serious cause of gastrointestinal bleeding, typically affecting older adults. It involves an aberrant arteriole eroding the gastric mucosa, resulting in severe, recurrent bleeding that poses diagnostic and management challenges. We present a case report of massive gastrointestinal hemorrhage with hemodynamic instability associated with a Dieulafoy's lesion.

CASE PRESENTATION

A 55-year-old male with no significant medical history presented with gastrointestinal bleeding, showing signs of hematemesis and melena. He was hemodynamically unstable upon admission, with a hemoglobin level of 6 g/dL. After resuscitation and stabilization, an esophagogastroduodenoscopy revealed a 5 mm Dieulafoy lesion in the fundus, treated successfully with hemostatic clips. The patient had an uneventful recovery and was discharged on the fourth day, with normal follow-up at one year and no complications.

CLINICAL DISCUSSION

Dieulafoy's lesion, a rare cause of gastrointestinal bleeding, is found in 1-2 % of cases, primarily in males over 60 years old. First described by Dieulafoy, it results from an aberrant arteriole erosion, commonly in the upper stomach. Diagnosis is challenging during active bleeding and often requires multiple endoscopies. Mechanical hemostasis methods during endoscopy are effective, with recurrence rates of 8-10 %. Surgical intervention is reserved for severe, uncontrolled cases.

CONCLUSION

Dieulafoy's lesion, though rare, requires prompt diagnosis and effective endoscopic treatment to manage severe bleeding. Combining hemostatic techniques or surgical options may be necessary to address persistent cases and improve patient outcomes.

摘要

引言与重要性

Dieulafoy病变是胃肠道出血的一种罕见但严重的病因,通常影响老年人。它涉及一条异常的小动脉侵蚀胃黏膜,导致严重的、反复的出血,给诊断和治疗带来挑战。我们报告一例与Dieulafoy病变相关的伴有血流动力学不稳定的大量胃肠道出血病例。

病例介绍

一名55岁男性,无重大病史,出现胃肠道出血,表现为呕血和黑便。入院时他血流动力学不稳定,血红蛋白水平为6g/dL。经过复苏和稳定病情后,食管胃十二指肠镜检查发现胃底有一个5mm的Dieulafoy病变,用止血夹成功治疗。患者恢复顺利,于第四天出院,一年随访正常,无并发症。

临床讨论

Dieulafoy病变是胃肠道出血的罕见病因,在1%-2%的病例中发现,主要见于60岁以上男性。最初由Dieulafoy描述,它是由异常的小动脉侵蚀引起的,通常发生在上胃部。在活动性出血期间诊断具有挑战性,通常需要多次内镜检查。内镜检查期间的机械止血方法有效,复发率为8%-10%。手术干预仅适用于严重的、无法控制的病例。

结论

Dieulafoy病变虽然罕见,但需要及时诊断和有效的内镜治疗来处理严重出血。对于持续存在的病例,可能需要结合止血技术或手术选择,以改善患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9173/11745977/f5d41323aa0c/gr1.jpg

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