Borbély Ruben Zsolt, Teutsch Brigitta, Hegyi Péter
Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Department of Medical Imaging, Bajcsy-Zsilinszky Hospital and Clinic, Budapest, Hungary.
United European Gastroenterol J. 2025 Feb;13(1):86-96. doi: 10.1002/ueg2.12744. Epub 2025 Jan 1.
Splanchnic vein thrombosis (SVT) in pancreatic disease has a 20%-30% incidence rate, leading to increased mortality and complication rates. Therefore, the aim of this review is to summarize recent evidence about the incidence, risk factors, and management of pancreatic cancer, pancreatic cystic neoplasm-, and pancreatitis-related SVT. Doppler ultrasound should be the first imaging choice, followed by contrast-enhanced computed tomography or magnetic resonance imaging. Data regarding SVT treatment in acute pancreatitis and pancreatic cancer are scarce; however, for venous thromboembolism treatment, direct oral anticoagulants and low molecular weight heparin have been effective. Further trials must investigate the length of anticoagulant treatment and the need for interventional radiological procedures.
胰腺疾病中的内脏静脉血栓形成(SVT)发病率为20% - 30%,会导致死亡率和并发症发生率升高。因此,本综述的目的是总结关于胰腺癌、胰腺囊性肿瘤及胰腺炎相关SVT的发病率、危险因素和治疗的最新证据。多普勒超声应作为首选影像学检查,其次是对比增强计算机断层扫描或磁共振成像。关于急性胰腺炎和胰腺癌中SVT治疗的数据较少;然而,对于静脉血栓栓塞的治疗,直接口服抗凝剂和低分子量肝素已被证明有效。进一步的试验必须研究抗凝治疗的时长以及介入放射学程序的必要性。