手部和腕部骨折愈合增强的内在和外在方法
Intrinsic and Extrinsic Methods for Augmenting Fracture Healing in the Hand and Wrist.
作者信息
Borole Aryan, Trubiano Jack, Viqueira Marissa, Kalahasti Karan, Stamos Thomas, Kirschenbaum David, Katt Brian M
机构信息
Department of Orthopedic Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
出版信息
Cureus. 2024 Dec 2;16(12):e74972. doi: 10.7759/cureus.74972. eCollection 2024 Dec.
Abstract
This review examines intrinsic and extrinsic augmentation techniques for uniting hand and upper extremity fractures, including bone morphogenic proteins (BMPs), platelet-rich plasma (PRP), low-intensity pulsed ultrasound (LIPUS), and pulsed electromagnetic fields (PEMF). While BMPs, PRP, LIPUS, and PEMF show potential in accelerating bone healing and reducing nonunion rates, their clinical adoption is limited by high costs and inconsistent results. This paper focuses on understanding the efficacy of these techniques, their drawbacks, and potential next steps for the field.
摘要
本综述探讨了用于手部和上肢骨折愈合的内源性和外源性增强技术，包括骨形态发生蛋白（BMPs）、富血小板血浆（PRP）、低强度脉冲超声（LIPUS）和脉冲电磁场（PEMF）。虽然BMPs、PRP、LIPUS和PEMF在加速骨愈合和降低骨不连发生率方面显示出潜力，但其临床应用受到高成本和结果不一致的限制。本文着重于了解这些技术的疗效、缺点以及该领域潜在的下一步发展方向。
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