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非体外循环冠状动脉旁路移植术治疗左心室射血分数降低的不稳定型心绞痛后早期左心室血栓形成1例罕见病例

A Rare Case of Early Left Ventricular Thrombus Development After Off-Pump Coronary Artery Bypass Grafting for Unstable Angina Pectoris With Reduced Left Ventricular Ejection Fraction.

作者信息

Machii Yojiro, Hayashi Yuki, Harada Atsushi, Ezawa Yuzo, Tanaka Masashi

机构信息

Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, JPN.

出版信息

Cureus. 2024 Dec 1;16(12):e74938. doi: 10.7759/cureus.74938. eCollection 2024 Dec.

Abstract

Left ventricular (LV) thrombus is a serious complication of myocardial infarction (MI) that can lead to a fetal systemic embolism. Although coronary artery bypass graft surgery (CABG) after MI is widely performed, to our knowledge, there are no reports of LV thrombus in the early postoperative period. Here, we report a rare case of a 70-year-old man who underwent off-pump coronary artery bypass grafting (OPCAB) for unstable angina pectoris with reduced left ventricular ejection fraction (LVEF). An LV thrombus (13 mm × 12 mm) was incidentally discovered on an echocardiography 7 days after OPCAB. We administered an oral anticoagulant (OAC) and observed resolution of the thrombus five months post-surgery. In the present case, factors such as low LVEF, infarcted lesion at the apex, and hypercoagulable state due to systemic inflammation after CABG likely contributed to LV thrombus development. This case highlights that LV thrombus is a potential complication early after CABG; thus, careful follow-up is required during the early postoperative period. Prophylactic anticoagulant administration in the early postoperative period should be considered for patients at particularly high risk for LV thrombus.

摘要

左心室(LV)血栓是心肌梗死(MI)的一种严重并发症,可导致致命的全身性栓塞。尽管心肌梗死后冠状动脉旁路移植术(CABG)已广泛开展,但据我们所知,尚无术后早期左心室血栓的报道。在此,我们报告一例罕见病例,一名70岁男性因不稳定型心绞痛伴左心室射血分数(LVEF)降低接受非体外循环冠状动脉旁路移植术(OPCAB)。OPCAB术后7天,经超声心动图偶然发现左心室血栓(13mm×12mm)。我们给予口服抗凝剂(OAC),术后5个月观察到血栓溶解。在本病例中,低LVEF、心尖梗死病变以及CABG后全身炎症导致的高凝状态等因素可能促成了左心室血栓的形成。该病例突出表明左心室血栓是CABG术后早期的一种潜在并发症;因此,术后早期需要密切随访。对于左心室血栓特别高危的患者,应考虑在术后早期预防性应用抗凝剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ddb/11692004/059b681df9f0/cureus-0016-00000074938-i01.jpg

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