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新生儿后鼻孔闭锁的手术时机与支架置入

Surgical Timing and Stenting in Neonatal Choanal Atresia.

作者信息

Moon Seojin, Jeong Yeonsu, Rha Min Seok, Kim Chang-Hoon, Cho Hyung-Ju

机构信息

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Department of Otorhinolaryngology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.

出版信息

J Rhinol. 2024 Nov;31(3):162-167. doi: 10.18787/jr.2024.00036. Epub 2024 Nov 30.

Abstract

BACKGROUND AND OBJECTIVES

Congenital choanal atresia is a rare condition that occurs in approximately 1 in 7,000 to 8,000 live births and involves the obstruction of the posterior nasal airway. It may present as either unilateral or bilateral, with bilateral cases being more severe due to the risk of immediate neonatal respiratory distress. Bilateral congenital choanal atresia (BCCA) necessitates prompt medical intervention to prevent cyanosis and significant breathing difficulties. This study focuses on the timing of surgery, the duration of stent use, and postoperative care in patients with bilateral congenital choanal atresia who underwent endoscopic transnasal surgery. Unlike previous studies, this research emphasizes the efficacy of an extended stenting period and introduces novel stenting techniques aimed at reducing restenosis.

METHODS

From 2018 to 2021, three patients with BCCA underwent transnasal surgery that included the placement of stents. We retrospectively analyzed their medical records, focusing on the surgical outcomes in relation to the duration of stent placement and postoperative care. A novel approach was adopted, involving the use of customized stent sizes tailored to the specific anatomical factors of each patient, which facilitated improved neochoana maintenance.

RESULTS

The average interval from diagnosis to surgery was 3.6 weeks. Surgery was successful in all cases, and the stent was removed after 6 months. In all patients, stable neochoanae were maintained without significant restenosis. Additionally, we observed that maintaining a stent for a period longer than previously recommended significantly reduced the risk of restenosis compared to the shorter durations used in earlier studies.

CONCLUSION

Our study suggests that an extended stenting period of 6 months or more is crucial for maintaining long-term patency in patients with BCCA. This approach could lead to a more reliable stenting protocol and improved postoperative care, potentially establishing a new standard for managing BCCA.

摘要

背景与目的

先天性后鼻孔闭锁是一种罕见疾病,在每7000至8000例活产婴儿中约有1例发生,涉及后鼻孔气道阻塞。它可表现为单侧或双侧,双侧病例因有立即出现新生儿呼吸窘迫的风险而更为严重。双侧先天性后鼻孔闭锁(BCCA)需要及时的医学干预以预防发绀和严重呼吸困难。本研究聚焦于接受内镜经鼻手术的双侧先天性后鼻孔闭锁患者的手术时机、支架使用时长及术后护理。与既往研究不同,本研究强调延长支架置入期的有效性,并引入旨在减少再狭窄的新型支架技术。

方法

2018年至2021年,3例BCCA患者接受了包括放置支架的经鼻手术。我们回顾性分析了他们的病历,重点关注与支架放置时长及术后护理相关的手术结果。采用了一种新方法,即根据每位患者的特定解剖因素使用定制尺寸的支架,这有助于更好地维持新后鼻孔。

结果

从诊断到手术的平均间隔时间为3.6周。所有病例手术均成功,支架在6个月后取出。所有患者均维持了稳定的新后鼻孔,无明显再狭窄。此外,我们观察到,与早期研究中使用的较短时长相比,将支架维持较长时间可显著降低再狭窄风险。

结论

我们的研究表明,6个月或更长时间的延长支架置入期对于维持BCCA患者的长期通畅至关重要。这种方法可能会产生更可靠的支架置入方案并改善术后护理,有可能为BCCA的治疗确立新的标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69cb/11685918/e140699cd467/jr-2024-00036f1.jpg

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