Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Rutgers Robert Wood Johnson Medical School , New Brunswick, NJ , USA.
Front Pediatr. 2015 Jun 9;3:52. doi: 10.3389/fped.2015.00052. eCollection 2015.
Choanal atresia (CA) is a relatively uncommon but well-recognized condition characterized by the anatomical closure of the posterior choanae in the nasal cavity. Since the original description back in the early eighteenth century, there have been controversies regarding its exact pathogenesis, the optimal surgical approach, and the use of adjunct treatments such as post-surgical stenting and anti-neoplastic agents, despite of abundant literature available. The emergence and development of new technologies play a significant role in the management of this condition. This review provides a comprehensive clinical update on CA and identifies areas for future study based on the existing available literature.
后鼻孔闭锁(CA)是一种相对罕见但已被充分认识的疾病,其特征是鼻腔后部的后鼻孔解剖性闭锁。自 18 世纪初首次描述以来,尽管有大量的文献可供参考,但对于其确切的发病机制、最佳手术入路以及辅助治疗(如术后支架和抗肿瘤药物)的应用仍存在争议。新技术的出现和发展在该疾病的治疗中发挥着重要作用。本综述提供了 CA 的全面临床更新,并根据现有文献确定了未来研究的领域。