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Chromosome changes with time in lymphocytes after occupational exposure to toluene.

作者信息

Schmid E, Bauchinger M, Hauf R

出版信息

Mutat Res. 1985 Jan-Feb;142(1-2):37-9. doi: 10.1016/s0165-7992(85)80009-9.

DOI:10.1016/s0165-7992(85)80009-9
PMID:3974596
Abstract

Chromosome analyses were carried out in peripheral lymphocytes of 27 workers exposed to toluene in a rotogravure plant. At the time of blood sampling all of them had not been exposed to toluene for at least 4 months up to 5 years. Up to 2 years after cessation of exposure to toluene a higher incidence of chromatid-type aberrations could be observed than in controls. After longer post-exposure periods the aberration yields can no longer be distinguished from background level. No differences were revealed in SCE frequencies of smoking or non-smoking workers post toluene exposure compared with the corresponding controls.

摘要

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