环氧树脂对人体的细胞遗传学影响：取决于性别、年龄和暴露时间。
Cytogenetic effects of epoxy resin in man: dependence on sex, age and period of exposure.
作者信息
Sazonova L A, Suskov I I
出版信息
Mutat Res. 1985 Mar;155(3):127-9. doi: 10.1016/0165-1218(85)90130-2.
The cytogenetic analysis of 156 subjects occupationally exposed to epoxy resin has revealed sex-dependent differences: average frequencies of aberrant metaphases and chromosome breaks per cell were significantly higher in males than in females. No linear or other functional relationship between the frequency of aberrant metaphases and the period of exposure to the resin has been revealed. However, a significantly higher average frequency of aberrant metaphases was observed in the group of elderly workers with a long period of exposure. The distribution of individuals according to the frequency of aberrant metaphases in the control group does not differ significantly from Poisson's law, while in individuals exposed to epoxy resin it is closer to the normal distribution.
对156名职业性接触环氧树脂的受试者进行的细胞遗传学分析显示出性别差异：男性细胞中异常中期相和染色体断裂的平均频率显著高于女性。未发现异常中期相频率与树脂接触时间之间存在线性或其他函数关系。然而，在长期接触树脂的老年工人组中，观察到异常中期相的平均频率显著更高。对照组中个体根据异常中期相频率的分布与泊松定律无显著差异，而接触环氧树脂的个体则更接近正态分布。
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