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[合成树脂对人体的细胞遗传学效应]

[Cytogenetic effects of synthetic resins in man].

作者信息

Sazonova L A, Suskov I I

出版信息

Genetika. 1982 Jul;18(7):1201-3.

PMID:6889555
Abstract

The cytogenetic analysis of persons occupationally exposed to synthetic resins has revealed the reliable increase in the average frequency of cells with chromosome aberrations. The value obtained were 5,5% (146 persons) for epoxide resin, 6,1% (52 persons) for polyvinylchloride, 5,0% (31 persons) for phenolformaldehyde and 2,4% (74 persons) in the control. The average rate of aberrant chromosomes was 0,054 to 0,065 per cell for all synthetic resins, which differed significantly from the control. The average rate of chromosome breaks per chromosome did not reliably differ from that in the control.

摘要

对职业性接触合成树脂人员的细胞遗传学分析显示,染色体畸变细胞的平均频率有可靠增加。环氧树脂的该值为5.5%(146人),聚氯乙烯为6.1%(52人),酚醛树脂为5.0%(31人),对照组为2.4%(74人)。所有合成树脂的异常染色体平均发生率为每细胞0.054至0.065条,与对照组有显著差异。每条染色体的染色体断裂平均发生率与对照组无可靠差异。

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