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职业性接触环氧树脂无细胞遗传学效应。

Occupational exposure to epoxy resins has no cytogenetic effect.

作者信息

Mitelman F, Fregert S, Hedner K, Hillbertz-Nilsson K

出版信息

Mutat Res. 1980 Apr;77(4):345-8. doi: 10.1016/0165-1218(80)90006-3.

Abstract

Cytogenetic evaluation was performed of peripheral lymphocytes from 18 workers currently exposed to epoxy resins of the type diglycidyl ether bisphenol-A (DGEBA). 9 workers were exposed to low molecular (average MW less than 900) and 9 to high molecular (average MW about 2000) epoxy resins. The results were compared with an equal number of control individuals matched for sex and age. There was no difference in chromosomal aberration frequency between the controls and the groups exposed to epoxy resin. Thus, this study gave no indication that exposure to epoxy resin produces visible damage to the chromosomes.

摘要

对18名目前接触双酚A二缩水甘油醚(DGEBA)型环氧树脂的工人的外周血淋巴细胞进行了细胞遗传学评估。9名工人接触低分子(平均分子量小于900)环氧树脂,9名工人接触高分子(平均分子量约2000)环氧树脂。将结果与相同数量的在性别和年龄上匹配的对照个体进行比较。对照组与接触环氧树脂组之间的染色体畸变频率没有差异。因此,本研究没有表明接触环氧树脂会对染色体产生明显损伤。

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