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衍射人工晶状体轮廓的非接触无透镜全息重建。

Non-contact lensless holographic reconstruction of diffractive intraocular lenses profiles.

作者信息

Vila-Andrés Rosa, Martínez-Espert Anabel, Furlan Walter D, Esteve-Taboada José J, Micó Vicente

机构信息

Faculty of Physics, Department of Optics and Optometry and Vision Sciences, Universitat de València, Burjassot, Spain.

出版信息

Sci Rep. 2025 Jan 2;15(1):566. doi: 10.1038/s41598-024-84363-7.

DOI:10.1038/s41598-024-84363-7
PMID:39747332
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11696758/
Abstract

A lensless compact arrangement based on digital in-line holography under Gabor's regime is proposed as a novel contactless method to assess the profile of multifocal intraocular lenses (MIOLs) which are conformed by several diffractive rings. Diffractive MIOLs are a widely adopted ophthalmologic option for the correction of presbyopia in patients undergoing cataract surgery. The MIOL optical design might introduce non-negligible optical performance differences between lenses as well as the introduction of undesirable photic phenomena (such as halos and glare) affecting the vision of users. Therefore, the customized topographic control of each manufactured MIOL model, along with the advancement of optical simulation routines, is increasingly necessary to provide users with optimized performance of these implanted optics, as well as predictable and realistic expectations of their future vision with these solutions. In this manuscript, experimental results of the reconstruction of different smooth and highly edged diffractive profiles from a pair of commercially available MIOLs are presented. Besides, a study evaluating the convergence and robustness of the proposed iterative phase-retrieval routine based on a modified classical Gerchberg-Saxton algorithm is performed. These results provide experimental validation of the proposed technique for accurately measuring the optical profiles of MIOLs.

摘要

提出了一种基于加博尔模式下数字同轴全息术的无透镜紧凑装置,作为一种新型非接触式方法来评估由多个衍射环构成的多焦点人工晶状体(MIOL)的轮廓。衍射型MIOL是白内障手术患者矫正老花眼广泛采用的眼科选择。MIOL的光学设计可能会在不同晶状体之间引入不可忽视的光学性能差异,以及引入影响使用者视力的不良光学现象(如光晕和眩光)。因此,对每个制造的MIOL模型进行定制的地形控制,以及光学模拟程序的改进,对于为用户提供这些植入式光学器件的优化性能,以及对使用这些解决方案的未来视力提供可预测和现实的期望越来越必要。在本论文中,展示了从一对市售MIOL重建不同平滑和高边缘衍射轮廓的实验结果。此外,还进行了一项研究,评估基于改进的经典格尔奇贝格 - 萨克斯顿算法的迭代相位恢复程序的收敛性和鲁棒性。这些结果为所提出的准确测量MIOL光学轮廓的技术提供了实验验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/167eb391c045/41598_2024_84363_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/bebd508c92a3/41598_2024_84363_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/9db691b60172/41598_2024_84363_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/a854929bf22d/41598_2024_84363_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/2b30ea92f480/41598_2024_84363_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/173afa895c9a/41598_2024_84363_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/167eb391c045/41598_2024_84363_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/bebd508c92a3/41598_2024_84363_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/9db691b60172/41598_2024_84363_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/a854929bf22d/41598_2024_84363_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/2b30ea92f480/41598_2024_84363_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/173afa895c9a/41598_2024_84363_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dd/11696758/167eb391c045/41598_2024_84363_Fig6_HTML.jpg

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本文引用的文献

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Opt Express. 2024 Jul 29;32(16):28666-28680. doi: 10.1364/OE.525986.
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Soft Contact Lens Engraving Characterization by Wavefront Holoscopy.基于波前全息术的软性隐形眼镜刻蚀特性分析
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PLoS One. 2023 Sep 8;18(9):e0291103. doi: 10.1371/journal.pone.0291103. eCollection 2023.
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BMJ Open Ophthalmol. 2023 Jan;8(1). doi: 10.1136/bmjophth-2022-001122.
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Optical performance of a new design of a trifocal intraocular lens based on the Devil's diffractive lens.基于魔鬼衍射透镜的新型三焦点人工晶状体的光学性能
Biomed Opt Express. 2023 Apr 28;14(5):2365-2374. doi: 10.1364/BOE.487812. eCollection 2023 May 1.
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Single-shot wavelength-multiplexed phase microscopy under Gabor regime in a regular microscope embodiment.在常规显微镜装置中的 Gabor regime 下的单次波长复用相显微镜。
Sci Rep. 2023 Mar 14;13(1):4257. doi: 10.1038/s41598-023-31300-9.
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Multi-Illumination Single-Holographic-Exposure Lensless Fresnel (MISHELF) Microscopy: Principles and Biomedical Applications.多光照单全息曝光无透镜菲涅耳(MISHELF)显微镜:原理与生物医学应用。
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