Li Bing, Li Junping, Sun Chao, Sun Yaodong, Zhang Zhiqiang
Department of Urology, Tianjin Medical University General Hospital, Tianjin, China.
Department of Oncology, Zibo City Municipal Hospital, Zibo, China.
Sci Rep. 2025 Jan 2;15(1):222. doi: 10.1038/s41598-024-83960-w.
To investigate the relationship between the Chinese Visceral Adiposity Index (CVAI) and the risk of developing Benign Prostatic Hyperplasia (BPH). Using data from the China Health and Retirement Longitudinal Study (CHARLS), we included 3,295 men aged 45 years and older. Multivariate logistic regression and restricted cubic spline models were employed to analyze the association between CVAI and the risk of BPH. During the 4-year follow-up period, 267 cases of BPH were identified. CVAI was positively associated with the risk of developing BPH (OR = 1.23, 95% CI: 1.07-1.42), with a significant dose-response relationship (P < 0.001). Stratified analysis showed that the effect of CVAI on BPH risk was consistent across various subgroups. There is a positive correlation between CVAI and the risk of developing BPH. Managing visceral fat content and maintaining a healthy fat distribution pattern may help reduce the risk of BPH.
为研究中国内脏脂肪指数（CVAI）与良性前列腺增生（BPH）发病风险之间的关系。利用中国健康与养老追踪调查（CHARLS）的数据，我们纳入了3295名45岁及以上的男性。采用多因素逻辑回归和受限立方样条模型分析CVAI与BPH发病风险之间的关联。在4年的随访期内，共确诊267例BPH病例。CVAI与BPH发病风险呈正相关（OR = 1.23，95%CI：1.07 - 1.42），具有显著的剂量反应关系（P < 0.001）。分层分析表明，CVAI对BPH风险的影响在各个亚组中是一致的。CVAI与BPH发病风险之间存在正相关。控制内脏脂肪含量并维持健康的脂肪分布模式可能有助于降低BPH的风险。
