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接触细颗粒物及其成分会导致肥胖:社会经济地位的作用。

Exposure to PM and its components leads to obesity: role of socioeconomic status.

作者信息

Peng Yindi, Zhao Yamin, Wang Minzhen, He Yingqian, Zhang Lulu, Zhao Yanan, Liu Jing, Zheng Shan

机构信息

Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, 199 Donggang West Road, 730000, Lanzhou City, Gansu Province, China.

出版信息

Sci Rep. 2025 Jan 2;15(1):114. doi: 10.1038/s41598-024-83923-1.

Abstract

Exposure to air pollutants is linked to an increased risk of obesity, and socioeconomic status (SES) could modulate this risk. We employed the "Jinchang Cohort" as a platform to investigate the influence of SES (education level, monthly income per household, and marital status) on the obesity risk associated with PM and its constituents. Study has demonstrated that air pollutant exposure enhances the likelihood of overweight/obesity, with a risk ratio (HR) of 1.229 for each quartile increase in PM concentration (95% CI: 1.137-1.328, P < 0.05). The risk of overweight/obesity rises with pollutant levels across various SES strata, with the effect being most marked among those with higher SES. For instance, the HRs and 95% CIs for overweight/obesity with each quartile increase in SO concentration were 1.338 (1.207-1.484), 1.311 (1.121-1.533), and 2.224 (1.823, 2.714) at low, medium, and high SES levels, respectively (all P < 0.05). An interaction between air pollutants and SES was observed in the context of obesity risk, with RERIs of 0.723 (0.473-0.973) and 0.562 (0.268-0.856) for medium-high SES levels and high NO exposure, respectively (both P < 0.05). These findings have practical implications. Public health campaigns could be launched to raise awareness among higher SES individuals about the obesity risk associated with air pollutants and encourage them to adopt preventive measures such as using air purifiers and increasing physical activity.

摘要

接触空气污染物与肥胖风险增加有关,社会经济地位(SES)可能会调节这种风险。我们以“金昌队列”为平台,研究SES(教育水平、家庭月收入和婚姻状况)对与颗粒物(PM)及其成分相关的肥胖风险的影响。研究表明,接触空气污染物会增加超重/肥胖的可能性,PM浓度每增加一个四分位数,风险比(HR)为1.229(95%置信区间:1.137 - 1.328,P < 0.05)。在不同SES阶层中,超重/肥胖风险随污染物水平升高而增加,在SES较高的人群中影响最为明显。例如,在低、中、高SES水平下,SO浓度每增加一个四分位数,超重/肥胖的HR及95%置信区间分别为1.338(1.207 - 1.484)、1.311(1.121 - 1.533)和2.224(1.823,2.714)(均P < 0.05)。在肥胖风险方面观察到空气污染物与SES之间存在交互作用,中高SES水平且高NO暴露时的相对超额危险度分别为0.723(0.473 - 0.973)和0.562(0.268 - 0.856)(均P < 0.05)。这些发现具有实际意义。可以开展公共卫生运动,提高SES较高人群对与空气污染物相关的肥胖风险的认识,并鼓励他们采取预防措施,如使用空气净化器和增加体育活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bb/11696562/efdb8e7cff58/41598_2024_83923_Fig1_HTML.jpg

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