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1
Sustained weight reduction following 12 weeks of intermittent fasting intervention in people with insulin-treated type 2 diabetes-Two-year follow-up of the randomised controlled InterFast-2 trial.胰岛素治疗的2型糖尿病患者间歇性禁食干预12周后体重持续减轻——随机对照InterFast-2试验的两年随访
Diabetes Obes Metab. 2025 Mar;27(3):1605-1608. doi: 10.1111/dom.16158. Epub 2025 Jan 2.
2
INTERmittent FASTing in people with insulin-treated type 2 diabetes mellitus - the INTERFAST-2 study protocol.《接受胰岛素治疗的 2 型糖尿病患者间歇性禁食：INTERFAST-2 研究方案》。
Diabet Med. 2022 Jun;39(6):e14813. doi: 10.1111/dme.14813. Epub 2022 Feb 28.
3
Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)-A Randomized Controlled Trial.接受胰岛素治疗的 2 型糖尿病患者间断性禁食的疗效和安全性（INTERFAST-2）-一项随机对照试验。
Diabetes Care. 2023 Feb 1;46(2):463-468. doi: 10.2337/dc22-1622.
4
Intermittent Fasting After ST-Segment-Elevation Myocardial Infarction Improves Left Ventricular Function: The Randomized Controlled INTERFAST-MI Trial.ST 段抬高型心肌梗死患者接受间歇性禁食后左心室功能得到改善：一项随机对照试验 INTERFAST-MI 研究。
Circ Heart Fail. 2024 May;17(5):e010936. doi: 10.1161/CIRCHEARTFAILURE.123.010936. Epub 2024 May 2.
5
Effect of intermittent fasting after ST-elevation myocardial infarction on left ventricular function: study protocol of a pilot randomised controlled trial (INTERFAST-MI).ST 段抬高型心肌梗死患者行间歇性禁食对左心室功能的影响：一项先导随机对照试验（INTERFAST-MI）的研究方案。
BMJ Open. 2022 Apr 7;12(4):e050067. doi: 10.1136/bmjopen-2021-050067.
6
Effects of dietary interventions and intermittent fasting on HDL function in obese individuals with T2DM: a randomized controlled trial.膳食干预和间歇性禁食对 T2DM 肥胖个体 HDL 功能的影响：一项随机对照试验。
Cardiovasc Diabetol. 2024 Sep 12;23(1):339. doi: 10.1186/s12933-024-02426-5.
7
Study protocol for the Shifting Weight using Intermittent Fasting in night shift workers (SWIFt) study: a three-arm randomised controlled trial comparing three weight loss strategies in night shift workers with obesity.夜间工作肥胖者采用间歇性禁食来调整体重的研究方案（SWIFt 研究）：一项三臂随机对照试验，比较三种减肥策略对夜间工作肥胖者的效果。
BMJ Open. 2022 Apr 26;12(4):e060520. doi: 10.1136/bmjopen-2021-060520.
8
Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus.胰岛素促泌剂用于预防或延缓2型糖尿病高危人群发生2型糖尿病及其相关并发症。
Cochrane Database Syst Rev. 2016 Oct 17;10(10):CD012151. doi: 10.1002/14651858.CD012151.pub2.
9
Knockdown of angiopoietin-like 2 mimics the benefits of intermittent fasting on insulin responsiveness and weight loss.敲低血管生成素样蛋白 2 可模拟间歇性禁食对胰岛素敏感性和体重减轻的益处。
Exp Biol Med (Maywood). 2018 Jan;243(1):45-49. doi: 10.1177/1535370217745505. Epub 2017 Dec 1.
10
Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.基层医疗主导的体重管理干预措施对 2 型糖尿病缓解的持久性：DIRECT 开放性标签、整群随机试验的 2 年结果。
Lancet Diabetes Endocrinol. 2019 May;7(5):344-355. doi: 10.1016/S2213-8587(19)30068-3. Epub 2019 Mar 6.

本文引用的文献

1
Evidence-based European recommendations for the dietary management of diabetes.欧洲基于证据的糖尿病饮食管理建议。
Diabetologia. 2023 Jun;66(6):965-985. doi: 10.1007/s00125-023-05894-8.
2
Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)-A Randomized Controlled Trial.接受胰岛素治疗的 2 型糖尿病患者间断性禁食的疗效和安全性（INTERFAST-2）-一项随机对照试验。
Diabetes Care. 2023 Feb 1;46(2):463-468. doi: 10.2337/dc22-1622.
3
The Association Between Sustained HbA1c Control and Long-Term Complications Among Individuals with Type 2 Diabetes: A Retrospective Study.2型糖尿病患者持续糖化血红蛋白（HbA1c）控制与长期并发症之间的关联：一项回顾性研究
Adv Ther. 2022 May;39(5):2208-2221. doi: 10.1007/s12325-022-02106-4. Epub 2022 Mar 22.
4
INTERmittent FASTing in people with insulin-treated type 2 diabetes mellitus - the INTERFAST-2 study protocol.《接受胰岛素治疗的 2 型糖尿病患者间歇性禁食：INTERFAST-2 研究方案》。
Diabet Med. 2022 Jun;39(6):e14813. doi: 10.1111/dme.14813. Epub 2022 Feb 28.
5
Benefits, mechanisms, and risks of intermittent fasting in metabolic syndrome and type 2 diabetes.间歇性禁食在代谢综合征和 2 型糖尿病中的益处、机制和风险。
J Physiol Biochem. 2022 May;78(2):295-305. doi: 10.1007/s13105-021-00839-4. Epub 2022 Jan 5.
6
IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045.国际糖尿病联盟（IDF）糖尿病地图集：2021 年全球、区域和国家糖尿病患病率估算值以及 2045 年预测值。
Diabetes Res Clin Pract. 2022 Jan;183:109119. doi: 10.1016/j.diabres.2021.109119. Epub 2021 Dec 6.
7
Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians.间歇性禁食：在糖尿病治疗中能发挥作用吗？文献综述及基层医疗医生指南
Clin Diabetes Endocrinol. 2021 Feb 3;7(1):3. doi: 10.1186/s40842-020-00116-1.
8
Metabolic Impact of Intermittent Fasting in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis of Interventional Studies.间歇性禁食对 2 型糖尿病患者代谢的影响：干预性研究的系统评价和荟萃分析。
J Clin Endocrinol Metab. 2021 Mar 8;106(3):902-911. doi: 10.1210/clinem/dgaa926.
9
Limited Evidence for the Health Effects and Safety of Intermittent Fasting Among Patients With Type 2 Diabetes.2型糖尿病患者间歇性禁食对健康影响及安全性的证据有限。
JAMA. 2020 Jul 28;324(4):341-342. doi: 10.1001/jama.2020.3908.
10
Improving type 2 diabetes mellitus glycaemic control through lifestyle modification implementing diet intervention: a systematic review and meta-analysis.通过生活方式改变实施饮食干预改善 2 型糖尿病患者的血糖控制：系统评价和荟萃分析。
Eur J Nutr. 2020 Jun;59(4):1313-1328. doi: 10.1007/s00394-019-02147-6. Epub 2019 Nov 28.

Sustained weight reduction following 12 weeks of intermittent fasting intervention in people with insulin-treated type 2 diabetes-Two-year follow-up of the randomised controlled InterFast-2 trial.

作者信息

Azhar Kehkishan, Ramirez-Obermayer Anna, Sourij Caren, Knoll Lisa, Andritz Eva, Kojzar Harald, Müller Alexander, Moser Othmar, Tripolt Norbert J, Pferschy Peter N, Aziz Faisal, Sourij Harald

机构信息

Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.

Department of Psychiatry, Psychosomatics and Psychotherapeutic Medicine, Division of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.

出版信息

Diabetes Obes Metab. 2025 Mar;27(3):1605-1608. doi: 10.1111/dom.16158. Epub 2025 Jan 2.

DOI:10.1111/dom.16158
PMID:39748228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11802388/
Abstract
摘要