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睡眠期周期性腿部运动:氯硝西泮治疗的效果

Periodic leg movements in sleep: effect of clonazepam treatment.

作者信息

Ohanna N, Peled R, Rubin A H, Zomer J, Lavie P

出版信息

Neurology. 1985 Mar;35(3):408-11. doi: 10.1212/wnl.35.3.408.

Abstract

Periodic leg movements in sleep were diagnosed in 8 patients with insomnia and in 12 patients with hypersomnia. Polysomnography did not reveal any difference in the number of leg movements in these groups, the mean duration of a leg movement, or the number of activity epochs. Those with insomnia, however, had a shorter intermovement interval than those with hypersomnia, with more leg movements in each activity epoch. Treatment with 0.5 to 2 mg clonazepam improved subjective complaints and decreased the number of leg movements without affecting the intermovement interval or movement duration.

摘要

在8例失眠患者和12例嗜睡症患者中诊断出睡眠期周期性腿部运动。多导睡眠图未显示这些组在腿部运动次数、腿部运动的平均持续时间或活动期次数上有任何差异。然而,失眠患者的运动间隔时间比嗜睡症患者短,每个活动期的腿部运动更多。使用0.5至2毫克氯硝西泮进行治疗可改善主观症状,并减少腿部运动次数,而不影响运动间隔时间或运动持续时间。

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