Kennedy D L, Baum C, Forbes M B
Obstet Gynecol. 1985 Mar;65(3):441-6.
The use of noncontraceptive estrogens and progestins, particularly in menopausal women, has been a subject of considerable controversy during the past decade. Reported is a review of overall trends in the use of these drugs from 1966 to 1983 and a more indepth qualitative and quantitative description of their use during 1983. The use of these estrogens and progestins appears to be increasing again. The estrogens are apparently being used at lower doses than in the past, and there is a trend toward using estrogens and progestins concomitantly. Exclusive of oral contraceptives, enough oral estrogen was purchased during 1983 to treat an average of 2.3 million people each day, while oral progestin purchases could have supplied 129,000 people daily.
在过去十年中，非避孕用雌激素和孕激素的使用，尤其是在绝经后妇女中的使用，一直是一个备受争议的话题。本文报告了1966年至1983年期间这些药物使用的总体趋势回顾，以及1983年期间对其使用情况更深入的定性和定量描述。这些雌激素和孕激素的使用似乎又在增加。雌激素的使用剂量显然比过去更低，并且存在同时使用雌激素和孕激素的趋势。不包括口服避孕药，1983年购买的口服雌激素足以平均每天治疗230万人，而口服孕激素的购买量每天可供12.9万人使用。
