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810纳米二极管激光与光动力疗法在减少种植体周围黏膜炎患者微生物群方面的抗菌疗效比较——一项体内研究

Comparison of the antibacterial efficacy of 810 nm diode laser and photodynamic therapy in reducing microbial flora in patients with peri-implant mucositis - An in vivo study.

作者信息

Siwach Poonam, Sanan Reshu, Nagpal Abhishek, Shetty Omkar Krishna, Bhardwaj Amit, Sharma Mukesh

机构信息

Department of Prosthodontics, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India.

Department of Periodontics, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India.

出版信息

J Indian Prosthodont Soc. 2025 Jan 1;25(1):40-45. doi: 10.4103/jips.jips_64_24. Epub 2025 Jan 3.

DOI:10.4103/jips.jips_64_24
PMID:39750007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11853942/
Abstract

AIM

The aim of this study was to investigate and compare the antimicrobial effects of an 810-nanometer diode laser, utilizing or not utilizing toluidine blue as a photosensitizer, in the management of peri-implant mucositis.

SETTINGS AND DESIGN

The present study was carried out in 30 implant sites in 15 patients with peri-implant mucositis with a specific inclusion and exclusion criteria. 15 sites were treated utilizing a diode laser (control group) and 15 with photodynamic therapy (test group) in a split-mouth format.

MATERIALS AND METHODS

Samples were taken from the gingival sulcus with the help of plastic curettes from control and test sites both at baseline and at 3 months for microbiological analysis.

STATISTICAL ANALYSIS USED

Shapiro-Wilk Test was used to check deviation from normality. Wilcoxon signed-rank test was used to analyse the two dependent groups.

RESULTS

Intragroup comparison was found to be statistically significant when compared at baseline and at 3 months in the photodynamic (P = 0.001) and diode laser groups (P = 0.001), respectively. No statistically significant reduction in bacterial count was found at baseline (P = 0.1) and at 3 months (P = 0.5) when the diode laser group and photodynamic group were compared with each other (intergroup).

CONCLUSION

Within the limitations of the study, it can be concluded that there is a definitive reduction in pathogenic bacteria with both interventions and PDT offers clinically visible benefits in the treatment of peri-implant mucositis.

摘要

目的

本研究旨在调查和比较810纳米二极管激光在使用或不使用甲苯胺蓝作为光敏剂的情况下,对种植体周围黏膜炎的抗菌效果。

设置与设计

本研究针对15例患有种植体周围黏膜炎的患者的30个种植位点进行,有特定的纳入和排除标准。采用双侧对照的方式,15个位点采用二极管激光治疗(对照组),15个位点采用光动力疗法(试验组)。

材料与方法

在基线和3个月时,使用塑料刮匙从对照组和试验组的牙龈沟采集样本,进行微生物分析。

所用统计分析方法

采用夏皮罗-威尔克检验来检查数据是否偏离正态分布。采用威尔科克森符号秩检验来分析两个相关组。

结果

光动力组(P = 0.001)和二极管激光组(P = 0.001)在基线和3个月时进行组内比较,差异均有统计学意义。二极管激光组和光动力组相互比较(组间)时,在基线时(P = 0.1)和3个月时(P = 0.5)细菌计数均未发现有统计学意义的降低。

结论

在本研究的局限性范围内,可以得出结论,两种干预措施均能使病原菌数量明显减少,并且光动力疗法在治疗种植体周围黏膜炎方面具有临床可见的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/7db14f5774d1/JIPS-25-40-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/0cb0b84ee36d/JIPS-25-40-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/e98be949c0be/JIPS-25-40-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/c715b887bcd1/JIPS-25-40-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/7db14f5774d1/JIPS-25-40-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/0cb0b84ee36d/JIPS-25-40-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/e98be949c0be/JIPS-25-40-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/c715b887bcd1/JIPS-25-40-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b801/11853942/7db14f5774d1/JIPS-25-40-g004.jpg

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J Clin Exp Dent. 2020 Jan 1;12(1):e13-e21. doi: 10.4317/medoral.56424. eCollection 2020 Jan.
2
Evaluation of Effectiveness of Photodynamic Therapy With Low-level Diode Laser in Nonsurgical Treatment of Peri-implantitis.低强度二极管激光光动力疗法在种植体周围炎非手术治疗中的疗效评估
J Lasers Med Sci. 2017 Summer;8(3):136-142. doi: 10.15171/jlms.2017.25. Epub 2017 Jun 27.
3
Comparison of the Antibacterial Effect of 810 nm Diode Laser and Photodynamic Therapy in Reducing the Microbial Flora of Root Canal in Endodontic Retreatment in Patients With Periradicular Lesions.
810纳米二极管激光与光动力疗法在根尖周病变患者根管再治疗中减少根管微生物群的抗菌效果比较
J Lasers Med Sci. 2016 Spring;7(2):99-104. doi: 10.15171/jlms.2016.17. Epub 2016 Mar 27.
4
Current concepts in the use of lasers in periodontal and implant dentistry.激光在牙周病学和种植牙科学中的应用现状
J Indian Soc Periodontol. 2015 Sep-Oct;19(5):490-4. doi: 10.4103/0972-124X.153471.
5
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J Clin Periodontol. 2015 Apr;42 Suppl 16:S152-7. doi: 10.1111/jcpe.12369.
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