Bell J A, Pearn J, Cohen G, Ford J, Halliday J, Martin N, Mulcahy M, Purvis-Smith S, Sutherland G
Prenat Diagn. 1985 Jan-Feb;5(1):53-8. doi: 10.1002/pd.1970050110.
This paper reports the results of a complete national survey to measure utilization rates of prenatal cytogenetic diagnosis (P.C.D.) in women of advanced maternal age in Australia. P.C.D. has been available throughout Australia for the last decade. Every laboratory in Australia providing a P.C.D. service for the years 1979-1982 took part in this study. Utilization rates (both National and State rates) by ages of mothers, are presented. Big interstate differences exist. The 1982 National P.C.D. utilization rate for pregnant women who were 40 years of age and over was 38.8 per cent, and this rate has shown an average annual increase of 9 per cent. In those four States which offered P.C.D. to pregnant women of 35 years or over the median utilization rate was 20 per cent. These Australian rates indicate an under-utilization of P.C.D. services with (in 1982) 50-80 per cent of 'at risk' women not being tested. Factors which influence this are discussed.
本文报告了一项全面的全国性调查结果,该调查旨在衡量澳大利亚高龄产妇的产前细胞遗传学诊断(P.C.D.)利用率。在过去十年中,澳大利亚各地均可进行P.C.D.检测。1979年至1982年期间,澳大利亚每个提供P.C.D.服务的实验室都参与了这项研究。文中列出了按母亲年龄划分的利用率(全国和各州的利用率)。州与州之间存在很大差异。1982年,40岁及以上孕妇的全国P.C.D.利用率为38.8%,且该比率平均每年增长9%。在为35岁及以上孕妇提供P.C.D.检测的四个州中,中位利用率为20%。这些澳大利亚的比率表明P.C.D.服务利用不足,在1982年,有50%至80%的“高危”女性未接受检测。文中讨论了影响这一情况的因素。