Santhoshkumar P, Ramu Dheetchanya, Mahalakshmi L, Moses J A
Computational Modeling and Nanoscale Processing Unit, Department of Food Process Engineering, National Institute of Food Technology Entrepreneurship and Management, Thanjavur (NIFTEM-T), Ministry of Food Processing Industries, Government of India, Thanjavur, 613005, Tamil Nadu, India.
Computational Modeling and Nanoscale Processing Unit, Department of Food Process Engineering, National Institute of Food Technology Entrepreneurship and Management, Thanjavur (NIFTEM-T), Ministry of Food Processing Industries, Government of India, Thanjavur, 613005, Tamil Nadu, India.
Biosens Bioelectron. 2025 Mar 15;272:117059. doi: 10.1016/j.bios.2024.117059. Epub 2024 Dec 10.
A recently minted field of 3D-printed edible electronics (EEs) represents a cutting-edge convergence of edible electronic devices and 3D printing technology. This review presents a comprehensive view of this emerging discipline, which has gathered significant scientific attention for its potential to create a safe, environmentally friendly, economical, and naturally degraded inside the human body. EEs have the potential to be used as medical and health devices to monitor physiological conditions and possibly treat diseases. These edible devices include different components, such as sensors, actuators, and other electronic elements, all made from edible ingredients such as sugars, proteins, polysaccharides, polymers, and others. Among the different fabrication approaches, 3D printing can provide reliable solutions to specific requirements. The concept of EEs has the potential to transform healthcare, providing more convenient, less invasive alternatives and personalized, customizable products for patients that beat traditional manufacturing methods. While the potential is enormous, there are critical challenges, notably ensuring the long-term stability, and regulatory and safety of these devices within the human body. Accordingly, a detailed understanding of the underlying concepts, fabrication approaches, design considerations, and action in the body/application range has been presented. As an evolving field, there is ample scope for research and multiple challenges must be addressed; these are elaborated towards the concluding sections of this article.
新兴的3D打印可食用电子产品（EEs）领域代表了可食用电子设备与3D打印技术的前沿融合。本综述全面介绍了这一新兴学科，该学科因其在人体内创造安全、环保、经济且可自然降解产品的潜力而受到了科学界的广泛关注。EEs有潜力用作医疗和健康设备，以监测生理状况并可能治疗疾病。这些可食用设备包括不同的组件，如传感器、致动器和其他电子元件，它们均由糖、蛋白质、多糖、聚合物等可食用成分制成。在不同的制造方法中，3D打印能够为特定需求提供可靠的解决方案。EEs的概念有潜力变革医疗保健，为患者提供比传统制造方法更便捷、侵入性更小的替代方案以及个性化、可定制的产品。尽管潜力巨大，但也存在重大挑战，尤其是要确保这些设备在人体内的长期稳定性以及监管和安全性。因此，本文详细阐述了其基本概念、制造方法、设计考量以及在体内的作用/应用范围。作为一个不断发展的领域，有大量的研究空间，必须应对多个挑战；本文结尾部分将详细阐述这些挑战。
