George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30024, USA; IEN Center for Wearable Intelligent Systems and Healthcare at the Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Department of Mechanical Engineering, Chungnam National University, 99 Daehak-Ro, Yuseong-Gu, Daejeon, 34134, Republic of Korea.
Biosens Bioelectron. 2024 Aug 1;257:116302. doi: 10.1016/j.bios.2024.116302. Epub 2024 Apr 17.
This review article focuses on the recent printing technological progress in healthcare, underscoring the significant potential of implantable devices across diverse applications. Printing technologies have widespread use in developing health monitoring devices, diagnostic systems, and surgical devices. Recent years have witnessed remarkable progress in fabricating low-profile implantable devices, driven by advancements in printing technologies and nanomaterials. The importance of implantable biosensors and bioelectronics is highlighted, specifically exploring printing tools using bio-printable inks for practical applications, including a detailed examination of fabrication processes and essential parameters. This review also justifies the need for mechanical and electrical compatibility between bioelectronics and biological tissues. In addition to technological aspects, this article delves into the importance of appropriate packaging methods to enhance implantable devices' performance, compatibility, and longevity, which are made possible by integrating cutting-edge printing technology. Collectively, we aim to shed light on the holistic landscape of implantable biosensors and bioelectronics, showcasing their evolving role in advancing healthcare through innovative printing technologies.
这篇综述文章聚焦于医疗保健领域的最新打印技术进展，强调了可植入设备在各种应用中的巨大潜力。打印技术在开发健康监测设备、诊断系统和手术设备方面有广泛的应用。近年来，由于打印技术和纳米材料的进步，可制造出低轮廓的可植入设备，这方面取得了显著进展。本文强调了可植入生物传感器和生物电子学的重要性，特别探讨了使用可生物打印墨水的打印工具在实际应用中的应用，包括对制造工艺和基本参数的详细检查。本文还证明了生物电子学和生物组织之间的机械和电气兼容性的必要性。除了技术方面，本文还探讨了适当的封装方法的重要性，这些方法可以通过集成先进的打印技术来提高可植入设备的性能、兼容性和寿命。总的来说，我们旨在全面了解可植入生物传感器和生物电子学的情况，展示它们通过创新的打印技术在推动医疗保健方面的不断发展的作用。
