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[美拉汀对大鼠下丘脑在辐射后晚期儿茶酚胺代谢正常化的作用]

[Use of meradin for normalizing catecholamine metabolism in the rat hypothalamus at late periods following irradiation].

作者信息

Prokudina E A, Bazanova N V, Borovitskaia A E

出版信息

Radiobiologiia. 1985 Jan-Feb;25(1):103-5.

PMID:3975363
Abstract

Meradine administered in a dose of 2 mg/kg during 10 days 10-12 months after irradiation with a dose of 4 Gy normalized the catecholamine metabolism in rat hypothalamus. The content of noradrenaline was restored as early as 24 h and that of DOPA and dopamine, 1 month after the cessation of meradine injection.

摘要

在以4 Gy剂量照射后10 - 12个月期间，以2 mg/kg的剂量连续10天给予美拉地定，可使大鼠下丘脑的儿茶酚胺代谢恢复正常。去甲肾上腺素的含量早在24小时就恢复了，而多巴和多巴胺的含量在美拉地定注射停止后1个月恢复。

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Radiobiologiia. 1985 Jan-Feb;25(1):103-5.
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