Bazanova N V, Borovitskaia A E, Vershinina S F, Prokudina E A
Radiobiologiia. 1984 Jul-Aug;24(4):534-6.
In this work, the authors have made an attempt to correct pharmacologically the disorders in the regulatory function of hypothalamus caused by gamma/neutron-irradiation. For this purpose purine derivatives, ethymisol and meradin, were used. These preparations were effective in correcting fully or partially the postirradiation shifts in the balance between the hypothalamus mediators, catecholamines, and their biosynthetic precursor, dioxyphenylalanine (DOPA). In addition, meradin increased the firmness of the bone regenerator in the traumatized extremity of the animal.
在这项研究中，作者尝试通过药理学方法纠正由γ/中子辐射引起的下丘脑调节功能紊乱。为此，使用了嘌呤衍生物乙嘧唑和美拉汀。这些制剂能完全或部分纠正辐射后下丘脑介质、儿茶酚胺及其生物合成前体二羟苯丙氨酸（DOPA）之间平衡的变化。此外，美拉汀增强了动物受伤肢体中骨再生组织的坚固性。
