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[位于受辐照和未受辐照红细胞血影不同部位的发色团之间的感应共振能量转移]

[Inductive-resonance energy transfer between chromophores localized in different parts of irradiated and nonirradiated erythrocyte ghosts].

作者信息

Fomenko B S, Dlimbetova G K, Akoev I G

出版信息

Radiobiologiia. 1985 Jan-Feb;25(1):12-5.

PMID:3975367
Abstract

A study was made of the inductive-resonance energy transfer between chromophore pairs, tryptophan--pyren, tryptophan--1.8-anilinonaphthalene sulfonate (ANS), puren--1.8-ANS, diphenylhexatrien--ethidium, and 1,8-ANS--ethidium, in irradiated (250 Gy) and nonirradiated preparations of erythrocytic membranes. The radiation--induced decrease in the energy transfer was noted in the pairs in which one of the chromophores was localized in a lipid phase. On the basis of the data obtained it is suggested that irradiation of membranes causes the lesions in them which lead to a reduction of the effective thickness of a hydrophobic part of the lipid bilayer.

摘要

对红细胞膜的辐照（250戈瑞）和未辐照制剂中色团对（色氨酸-芘、色氨酸-1.8-苯胺基萘磺酸盐（ANS）、芘-1.8-ANS、二苯基己三烯-溴化乙锭和1,8-ANS-溴化乙锭）之间的感应共振能量转移进行了研究。在其中一个色团位于脂质相的色团对中，观察到辐射诱导的能量转移减少。根据获得的数据表明，膜的辐照会导致膜中的损伤，从而导致脂质双层疏水部分的有效厚度减小。

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