[辐照及Fe2+引发脂质过氧化后红细胞血影的色氨酸荧光]
[Tryptophan fluorescence of erythrocyte ghosts following irradiation and Fe2+ initiation of lipid peroxidation].
作者信息
Fomenko B S
出版信息
Radiobiologiia. 1983 Sep-Oct;23(5):607-11.
It was shown that under the effect of Fe2+-initiated lipid peroxidation and ionizing radiation tryptophan fluorescence parameters (i.e. intensity and polarization) were subjected to similar changes. Shortly (15 min) after irradiation no changes were observed in the level of products reacting with thiobarbituric acid. It is concluded that the process and products of lipid peroxidation do not markedly contribute to the postirradiation alteration of tryptophan fluorescence. At the same time additional postirradiation damages to proteins can be attributed to activation of lipid peroxidation.
结果表明，在Fe2+引发的脂质过氧化作用和电离辐射下，色氨酸荧光参数（即强度和偏振）发生了类似的变化。照射后不久（15分钟），与硫代巴比妥酸反应的产物水平未观察到变化。得出的结论是，脂质过氧化的过程和产物对色氨酸荧光的辐射后改变没有显著贡献。同时，辐射后对蛋白质的额外损伤可归因于脂质过氧化的激活。
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