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清理思绪:囤积障碍的心理干预——一项系统综述与荟萃分析

Decluttering Minds: Psychological interventions for hoarding disorder - A systematic review and meta-analysis.

作者信息

O'Brien Emily, Laws Keith R

机构信息

School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.

School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.

出版信息

J Psychiatr Res. 2025 Jan;181:738-751. doi: 10.1016/j.jpsychires.2024.12.029. Epub 2024 Dec 27.

Abstract

BACKGROUND

Cognitive Behavioural Therapy (CBT) is conventionally considered the primary intervention for Hoarding Disorder (HD), yet various psychological interventions have recently emerged. This study, pre-registered at Prospero (CRD42023427534), aims to comprehensively assess a range of psychological interventions, including CBT, for reducing HD symptomatology.

METHODS

A systematic literature search using PubMed and SCOPUS identified 41 eligible studies comprising 47 samples (N = 1343). Risk of bias for RCTs was assessed using the Cochrane RoB2 tool, and methodological quality for all studies was evaluated using the Psychotherapy Outcome Study Methodology Rating Form (POMRF).

RESULTS

Pre-post effects revealed a large reduction in HD symptomatology (g = -1.09), sustained at follow-up in 18 studies (g = -1.12, N = 588). Additionally, 8 Randomized Controlled Trials (RCTs) demonstrated a substantial end-of-trial reduction in HD symptoms compared to controls (g = -0.75). Meta-regression found no moderating effects for: demographics, medication use, number of treatment sessions, or study quality. Similarly, no differences were observed between group and individual therapy, therapy with or without home visits, or CBT versus other psychological interventions.

CONCLUSION

This study confirms psychological therapies are effective in reducing hoarding symptoms, while indicating no superiority for CBT. Despite the benefits, symptoms often persist above the clinical cut-off for HD, highlighting the enduring clinical challenges in achieving symptomatic remission. The findings underscore the need to address methodological limitations and possible age and gender bias in future research to enhance the efficacy and inclusivity of psychological interventions for HD.

摘要

背景

认知行为疗法(CBT)传统上被认为是囤积障碍(HD)的主要干预方法,但最近出现了各种心理干预措施。本研究在国际前瞻性注册系统(Prospero,注册号CRD42023427534)上进行了预注册,旨在全面评估包括CBT在内的一系列心理干预措施对减轻HD症状的效果。

方法

通过PubMed和SCOPUS进行系统文献检索,确定了41项符合条件的研究,包含47个样本(N = 1343)。使用Cochrane偏倚风险评估工具(RoB2)评估随机对照试验(RCT)的偏倚风险,并使用心理治疗结果研究方法评分表(POMRF)评估所有研究的方法学质量。

结果

前后测效应显示HD症状有大幅减轻(g = -1.09),18项研究在随访时仍保持这一效果(g = -1.12,N = 588)。此外,8项随机对照试验表明,与对照组相比,试验结束时HD症状有显著减轻(g = -0.75)。元回归分析发现,人口统计学特征、药物使用、治疗疗程数或研究质量均无调节作用。同样,在团体治疗与个体治疗、有无家访的治疗、CBT与其他心理干预之间未观察到差异。

结论

本研究证实心理治疗对减轻囤积症状有效,但未显示CBT具有优越性。尽管有这些益处,但症状往往仍高于HD的临床临界值,这凸显了实现症状缓解方面持久的临床挑战。研究结果强调,未来研究需要解决方法学局限性以及可能存在的年龄和性别偏见,以提高HD心理干预的疗效和包容性。

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