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减少产前和产后妇女重金属暴露的饮食干预措施:一项系统综述

Dietary interventions to reduce heavy metal exposure in antepartum and postpartum women: a systematic review.

作者信息

Heo Su Ji, Moon Nalae, Kim Ju Hee

机构信息

College of Nursing Science, Kyung Hee University, Seoul, Korea.

出版信息

Womens Health Nurs. 2024 Dec;30(4):265-276. doi: 10.4069/whn.2024.12.16. Epub 2024 Dec 30.

DOI:10.4069/whn.2024.12.16
PMID:39756471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11700719/
Abstract

PURPOSE

Heavy metals, which are persistent in the environment and toxic, can accumulate in the body and cause organ damage, which may further negatively affect perinatal women and their fetuses. Therefore, this systematic review was conducted to evaluate the effectiveness of dietary interventions to reduce heavy metal exposure in antepartum and postpartum women.

METHODS

We searched five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) for randomized controlled trials that provided dietary interventions for antepartum and postpartum women. Quality assessments were conducted independently by two reviewers using the Cochrane Risk-of-Bias tool, a quality assessment tool for randomized controlled trials.

RESULTS

A total of seven studies were included. The studies were conducted in six countries, with interventions categorized into "nutritional supplements," "food supply," and "educational" strategies. Interventions involving nutritional supplements, such as calcium and probiotics, primarily reduced heavy metal levels in the blood and minimized toxicity. Food-based interventions, including specific fruit consumption, decreased heavy metal concentrations in breast milk. Educational interventions effectively promoted behavioral changes, such as adopting diets low in mercury. The studies demonstrated a low overall risk of bias, supporting the reliability of the findings. These strategies underscore the effectiveness of dietary approaches in mitigating heavy metal exposure and improving maternal and child health.

CONCLUSION

The main findings underscore the importance of dietary interventions in reducing heavy metal exposure. This emphasizes the critical role of nursing in guiding dietary strategies to minimize exposure risks, ultimately supporting maternal and fetal health during pregnancy.

摘要

目的

重金属在环境中具有持久性且有毒,可在体内蓄积并导致器官损伤,这可能会进一步对围产期妇女及其胎儿产生负面影响。因此,本系统评价旨在评估饮食干预对减少产前和产后妇女重金属暴露的有效性。

方法

我们检索了五个数据库(PubMed、Embase、Scopus、Web of Science和Cochrane图书馆),以查找为产前和产后妇女提供饮食干预的随机对照试验。由两名评价者使用Cochrane偏倚风险工具(一种随机对照试验的质量评估工具)独立进行质量评估。

结果

共纳入七项研究。这些研究在六个国家进行,干预措施分为“营养补充剂”、“食物供应”和“教育”策略。涉及营养补充剂(如钙和益生菌)的干预措施主要降低了血液中的重金属水平,并将毒性降至最低。基于食物的干预措施,包括特定水果的食用,降低了母乳中的重金属浓度。教育干预有效地促进了行为改变,如采用低汞饮食。这些研究显示总体偏倚风险较低,支持了研究结果的可靠性。这些策略强调了饮食方法在减轻重金属暴露和改善母婴健康方面的有效性。

结论

主要研究结果强调了饮食干预在减少重金属暴露方面的重要性。这突出了护理在指导饮食策略以最小化暴露风险方面的关键作用,最终在孕期支持母婴健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b882/11700719/82b8d77e3f24/whn-2024-12-16f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b882/11700719/7cb5bbaac0b4/whn-2024-12-16f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b882/11700719/82b8d77e3f24/whn-2024-12-16f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b882/11700719/7cb5bbaac0b4/whn-2024-12-16f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b882/11700719/82b8d77e3f24/whn-2024-12-16f2.jpg

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本文引用的文献

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Cadmium neurotoxicity: Insights into behavioral effect and neurodegenerative diseases.镉神经毒性:行为效应与神经退行性疾病的研究进展。
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