Tu Jiabin, Chen Hongkui, Zeng Qingfeng, Chen Liling, Guo Yansong, Chen Kaihong
Department of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, China (J.T., L.C., K.C.).
Department of Cardiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China (J.T., H.C., Y.G.).
Hypertension. 2025 Mar;82(3):498-508. doi: 10.1161/HYPERTENSIONAHA.124.24123. Epub 2025 Jan 6.
Obesity is a factor contributing to the occurrence of hypertension and a risk factor for adverse outcomes in populations with hypertension. The changes in the prevalence of obesity in populations with hypertension remain unclear. Investigating the changes in the prevalence of obesity in populations with hypertension can provide information for the treatment and management of hypertension.
The clinical data from adults aged ≥20 years with hypertension were extracted from the National Health and Nutrition Examination Survey 2001 to 2023. The primary outcome was the prevalence of obesity (body mass index≥30 kg/m). The trend in the prevalence of obesity among American adults with hypertension was evaluated via a trend test.
The age-standardized prevalence of obesity among populations with hypertension in America increased from 39.6% in 2001 to 55.4% in 2023 ( for trend<0.001). This trend was observed in men (35.4%-53.6%; for trend<0.001) and women (45.6%-57.7%; for trend<0.001) populations with hypertension. While the prevalence of grade II (35 kg/m≤body mass index<40 kg/m) and grade III obesity (body mass index≥40 kg/m) increased significantly in both sexes, the prevalence of grade I obesity (30 kg/m≤body mass index<35 kg/m) increased significantly only in men (23.2%-30.0%; for trend=0.003) and did not significantly change in women (22.2%-21.7%; for trend=0.135).
The prevalence of obesity among American adults with hypertension increased from 2001 to 2023. In men, the prevalence of grades I, II, and III obesity increased. Among women, the prevalence of only grades II and III obesity increased.
肥胖是导致高血压发生的一个因素,也是高血压人群不良结局的危险因素。高血压人群中肥胖患病率的变化尚不清楚。调查高血压人群中肥胖患病率的变化可为高血压的治疗和管理提供信息。
从2001年至2023年的美国国家健康和营养检查调查中提取年龄≥20岁的高血压成年患者的临床数据。主要结局是肥胖患病率(体重指数≥30kg/m²)。通过趋势检验评估美国高血压成年患者中肥胖患病率的趋势。
美国高血压人群中肥胖的年龄标准化患病率从2001年的39.6%增至2023年的55.4%(趋势P<0.001)。在男性(35.4% - 53.6%;趋势P<0.001)和女性(45.6% - 57.7%;趋势P<0.001)高血压人群中均观察到这一趋势。虽然II级(35kg/m²≤体重指数<40kg/m²)和III级肥胖(体重指数≥40kg/m²)的患病率在两性中均显著增加,但I级肥胖(30kg/m²≤体重指数<35kg/m²)的患病率仅在男性中显著增加(23.2% - 30.0%;趋势P = 0.003),而在女性中无显著变化(22.2% - 21.7%;趋势P = 0.135)。
2001年至2023年,美国高血压成年患者的肥胖患病率增加。在男性中,I级、II级和III级肥胖的患病率均增加。在女性中,仅II级和III级肥胖的患病率增加。