Ghoshal Gargi
Dr. S. S. Bhatnagar University Institute of Chemical Engineering & Technology, Panjab University, Chandigarh, 160014 India.
Food Sci Biotechnol. 2024 Sep 17;34(1):31-48. doi: 10.1007/s10068-024-01687-w. eCollection 2025 Jan.
Nanotechnology has gained recognition as the next uprising technology in numerous sectors, together with food industry and agriculture. Diminution of particle size to nanoscale range enhances the surface area, eventually surface-to-volume ratio, subsequently enhances their reactivity by several times, modifying optical, electrical, and mechanical features. Nanotechnology can also modify the aqueous solubility, thermal stability, and bioavailability in oral delivery of bioactive nutraceuticals. Recent research developed number of suitable delivery systems that provide effective site specific release of the nutraceuticals in control way for better utilization. Phospholipid, liposomes, niosome, emulsion, microemulsion/ nanoemulsions, ethosomes, SNEDDS, SLN based delivery vehicles, Nanostructured lipid carriers (NLCs) for nutraceutical delivery systems will be discussed in this review. Mainly the formulations, principle of the above carrier along with recent researches of those technologies will be discussed.
纳米技术已被公认为是食品工业和农业等众多领域的下一个崛起技术。将颗粒尺寸减小到纳米级范围可增加表面积,最终提高表面体积比,进而使其反应活性提高数倍,改变光学、电学和机械特性。纳米技术还可改变生物活性营养保健品口服给药时的水溶性、热稳定性和生物利用度。最近的研究开发了许多合适的递送系统,这些系统能够以可控方式有效地实现营养保健品的位点特异性释放,以实现更好的利用。本综述将讨论用于营养保健品递送系统的磷脂、脂质体、非离子表面活性剂泡囊、乳剂、微乳/纳米乳、醇质体、自乳化药物传递系统、基于固体脂质纳米粒的递送载体、纳米结构脂质载体(NLC)。主要将讨论上述载体的制剂、原理以及这些技术的最新研究情况。