Zhang Jeff F, Mix Michael D, Shapiro Anna, Babu Harish
Neurological Surgery, Upstate University Hospital, Syracuse, USA.
Radiation Oncology, Upstate University Hospital, Syracuse, USA.
Cureus. 2024 Dec 3;16(12):e75053. doi: 10.7759/cureus.75053. eCollection 2024 Dec.
Over the past two decades, despite the emergence of various novel therapies for glioblastoma, patient survival outcomes remain poor, particularly in the recurrent stage of the disease. Cesium-131 (Cs-131) brachytherapy presents a promising treatment option for patients with newly diagnosed and recurrent brain neoplasms, enabling the initiation of radiation therapy at the time of tumor resection. This approach eliminates the typical delay in therapy following surgery and the need for multiple return visits for fractionated external beam radiotherapy. This report describes a patient who underwent repeat Cs-131 brachytherapy implantations in the surgical cavity following the resection of a recurrent glioblastoma, achieving a good quality of life and survival of over 36 months.
在过去二十年中，尽管出现了各种针对胶质母细胞瘤的新型疗法，但患者的生存结果仍然很差，尤其是在疾病的复发阶段。铯-131（Cs-131）近距离放射治疗为新诊断和复发性脑肿瘤患者提供了一种有前景的治疗选择，能够在肿瘤切除时就开始放射治疗。这种方法消除了手术后典型的治疗延迟以及分次外照射放疗所需的多次复诊。本报告描述了一名复发性胶质母细胞瘤切除后在手术腔中接受重复Cs-131近距离放射治疗植入的患者，该患者获得了良好的生活质量并存活了超过36个月。
