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肾上腺腺瘤继发低钾血症性横纹肌溶解症:一例报告

Hypokalemia-Induced Rhabdomyolysis Secondary to Adrenal Adenoma: A Case Report.

作者信息

Rauf Faateh A, Pervaiz Zainab, Khan Taleah, Swaminathan Gowri, Trandafirescu Theo

机构信息

Internal Medicine, Icahn School of Medicine at Mount Sinai/New York City Health + Hospitals - Queens, New York City, USA.

Internal Medicine, Combined Military Hospital (CMH) Lahore Medical College and Institute of Dentistry, Lahore, PAK.

出版信息

Cureus. 2024 Dec 3;16(12):e75063. doi: 10.7759/cureus.75063. eCollection 2024 Dec.

Abstract

Adrenal adenoma, which leads to increased production of the hormone aldosterone, commonly presents as hypertension and hypokalemia. Rhabdomyolysis as a result of hypokalemia secondary to primary hyperaldosteronism is a rare but important complication with only a few reported cases. Low potassium levels can disrupt the regulation of arteriolar musculature, leading to reduced blood flow to skeletal muscles. This hypoperfusion may ultimately result in ischemia and cause rhabdomyolysis. We present the case of a woman with complaints of weakness and fatigue; laboratory reports showed hypokalemia and elevated serum creatine kinase (CK), leading to a diagnosis of hypokalemia-induced rhabdomyolysis. Further investigation revealed an adrenal adenoma, causing elevated aldosterone levels, which was then treated with a laparoscopic adrenalectomy, leading to the resolution of her symptoms.

摘要

肾上腺腺瘤会导致激素醛固酮分泌增加,通常表现为高血压和低钾血症。原发性醛固酮增多症继发低钾血症导致的横纹肌溶解是一种罕见但重要的并发症,仅有少数病例报道。低钾水平会破坏小动脉肌肉组织的调节,导致骨骼肌血流减少。这种灌注不足最终可能导致缺血并引起横纹肌溶解。我们报告一例女性患者,主诉为虚弱和疲劳;实验室检查报告显示低钾血症和血清肌酸激酶(CK)升高,诊断为低钾血症诱发的横纹肌溶解。进一步检查发现肾上腺腺瘤,导致醛固酮水平升高,随后行腹腔镜肾上腺切除术进行治疗,患者症状得以缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/376c/11698543/90323b23aa90/cureus-0016-00000075063-i01.jpg

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