Kamali Mohadese, Sarhadynejad Zarrin, Tajadini Haleh, Keikha Mojtaba, Salari Zohreh, Dehesh Tania, Lashkarizadeh Mahdiyeh, Esmaili Mitra
Faculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Faculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Iran J Nurs Midwifery Res. 2024 Nov 20;29(6):649-659. doi: 10.4103/ijnmr.ijnmr_311_23. eCollection 2024 Nov-Dec.
Bacterial Vaginosis (BV) is the most prevalent cause of vaginal infection among women. This study aimed to summarize the evidence related to the effectiveness of medicinal plants as an alternative therapy for the management of BV.
PubMed, Scopus, Cochrane Library, Web of Science, and Medline PubMed were systematically searched. Moreover, we searched Google Scholar to explore the possible effects of herbal treatments on BV in women of childbearing age up to 2022. All randomized clinical trials investigating the effects of medicinal plants as oral or vaginal monotherapy or in combination for BV treatment in women of childbearing age were included in this systematic review.
In total, 20 studies comprising 2685 participants were included in our review. The results show that combinations of herbal medicines such as and with metronidazole can have better results in the treatment of BV. Moreover, the main results show that some medicinal plant products alone such as Forzejehe and had therapeutic effects similar to metronidazole. Propolis and Brazilian pepper tree were effective in the treatment of BV, but they have less therapeutic effect than metronidazole.
To reduce the complications caused by chemical treatments and also the resistance of patients to these treatments, it seems necessary to use supportive treatments along with chemical drugs after the necessary approvals have been obtained.
细菌性阴道病（BV）是女性阴道感染最常见的原因。本研究旨在总结与药用植物作为治疗BV的替代疗法的有效性相关的证据。
对PubMed、Scopus、Cochrane图书馆、科学网和Medline PubMed进行系统检索。此外，我们还检索了谷歌学术，以探索截至2022年草药治疗对育龄妇女BV的可能影响。所有调查药用植物作为口服或阴道单一疗法或联合用于治疗育龄妇女BV的随机临床试验均纳入本系统评价。
我们的综述共纳入20项研究，涉及2685名参与者。结果表明，草药如[草药名称1]和[草药名称2]与甲硝唑联合使用在治疗BV方面可能有更好的效果。此外，主要结果表明，一些单独的药用植物产品如[药用植物产品名称1]和[药用植物产品名称2]具有与甲硝唑相似的治疗效果。蜂胶和巴西胡椒树在治疗BV方面有效，但它们的治疗效果不如甲硝唑。
为了减少化学治疗引起的并发症以及患者对这些治疗的耐药性，在获得必要批准后，似乎有必要在使用化学药物的同时使用支持性治疗。
