Moran S M, Jamison R L
West J Med. 1985 Jan;142(1):49-53.
Hyperglycemia may lower the plasma sodium concentration. Theoretical analyses have suggested that elevations in glucose concentration produce an invariant hyponatremic response. We propose, however, that change in plasma sodium concentration in response to hyperglycemia is variable and depends on (1) the distribution of total body water and solute, (2) the relationship between the gain of extracellular glucose and the loss of intracellular solute and (3) the intake and loss of solute and water. These factors are incorporated into a formulation of the relationship between the plasma sodium and glucose concentrations.
高血糖可能会降低血浆钠浓度。理论分析表明,葡萄糖浓度升高会产生恒定的低钠血症反应。然而,我们认为,高血糖引起的血浆钠浓度变化是可变的,并且取决于:(1)总体液和溶质的分布;(2)细胞外葡萄糖增加与细胞内溶质减少之间的关系;以及(3)溶质和水的摄入与丢失。这些因素被纳入血浆钠浓度与葡萄糖浓度之间关系的公式中。