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CT三维重建技术在肺结节良恶性鉴别诊断中的应用价值及结节分布特征

Application value of CT three-dimensional reconstruction technology in the identification of benign and malignant lung nodules and the characteristics of nodule distribution.

作者信息

Ji Guanghai, Liu Fei, Chen Zhiqiang, Peng Jie, Deng Hao, Xiao Sheng, Li Yun

机构信息

Department of Radiology, The First Affiliated Hospital of Yangtze University, No. 40 Jinlong Road, Shashi District, Jingzhou, Hubei, 434000, China.

Department of Radiology, The First Hospital Affiliated of Hainan Medical University, Haikou, Hainan, 570102, China.

出版信息

BMC Med Imaging. 2025 Jan 6;25(1):7. doi: 10.1186/s12880-024-01505-z.

Abstract

OBJECTIVE

The study aimed to evaluate the application value of computed tomography (CT) three-dimensional (3D) reconstruction technology in identifying benign and malignant lung nodules and characterizing the distribution of the nodules.

METHODS

CT 3D reconstruction was performed for lung nodules. Pathological results were used as the gold standard to compare the detection rates of various lung nodule signs between conventional chest CT scanning and CT 3D reconstruction techniques. Additionally, the differences in mean diffusion coefficient values and partial anisotropy index values between male and female patients were analyzed.

RESULTS

Pathologic confirmation identified 30 patients with benign lesions and 45 patients with malignant lesions. CT 3D reconstruction demonstrated higher diagnostic accuracy for lung nodule imaging signs compared to conventional CT scanning (P < 0.05). The mean diffusion coefficient values and partial anisotropy index values were lower in female patients compared to male patients in the lung nodule lesion area, lung perinodular edema area, and normal lung tissue (P < 0.05). Conventional CT scanning showed a benign accuracy rate of 63.33% and a malignant accuracy rate of 60.00%, whereas CT 3D imaging achieved a benign and malignant accuracy rate of 86.67% for both. The accuracy rates for CT 3D imaging were significantly higher than those for conventional CT scanning (P < 0.05).

CONCLUSION

CT 3D imaging technology demonstrates high diagnostic accuracy in differentiating benign from malignant lung nodules.

摘要

目的

本研究旨在评估计算机断层扫描(CT)三维(3D)重建技术在鉴别肺结节良恶性及描述结节分布特征方面的应用价值。

方法

对肺结节进行CT三维重建。以病理结果作为金标准,比较传统胸部CT扫描与CT三维重建技术对各种肺结节征象的检出率。此外,分析男性和女性患者在平均扩散系数值和部分各向异性指数值方面的差异。

结果

病理确诊30例良性病变患者和45例恶性病变患者。与传统CT扫描相比,CT三维重建对肺结节影像征象的诊断准确性更高(P < 0.05)。在肺结节病变区域、肺结节周围水肿区域和正常肺组织中,女性患者的平均扩散系数值和部分各向异性指数值低于男性患者(P < 0.05)。传统CT扫描的良性准确率为63.33%,恶性准确率为60.00%,而CT三维成像的良性和恶性准确率均为86.67%。CT三维成像的准确率显著高于传统CT扫描(P < 0.05)。

结论

CT三维成像技术在鉴别肺结节的良恶性方面具有较高的诊断准确性。

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