Raymond L
Soz Praventivmed. 1985;30(1):23-7. doi: 10.1007/BF02075724.
The present report discusses the main constraints influencing the choice in the method in the epidemiological approach of host factors and family factors. It briefly describes 3 of the usual methods in this field, i.e. the migrant studies, the twin studies and the family studies. The practical problems and the conceptual limitations met by each of these 3 methods are reviewed. A brief review of the literature provides an opportunity for examining the main misunderstandings between geneticists and epidemiologists in their study of human groups when analysing the role of such factors in the etiology of cancer.
本报告讨论了在宿主因素和家庭因素的流行病学研究方法中影响选择的主要制约因素。简要描述了该领域常用的三种方法,即移民研究、双胞胎研究和家庭研究。对这三种方法各自遇到的实际问题和概念局限进行了综述。对文献的简要回顾为审视遗传学家和流行病学家在研究人类群体、分析此类因素在癌症病因中的作用时存在的主要误解提供了契机。