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迁移与死亡率:对瑞典有移民双胞胎的芬兰双胞胎对进行的20年随访

Migration and mortality: a 20 year follow up of Finnish twin pairs with migrant co-twins in Sweden.

作者信息

Hammar N, Kaprio J, Hagström U, Alfredsson L, Koskenvuo M, Hammar T

机构信息

Division of Epidemiology, Institute of Environmental Medicine, Karolinska institutet, Stockholm, Sweden.

出版信息

J Epidemiol Community Health. 2002 May;56(5):362-6. doi: 10.1136/jech.56.5.362.

Abstract

STUDY OBJECTIVE

Finland has a higher mortality overall and for major causes of death than Sweden, primarily in men. The objective of this study was to analyse mortality in migrants from Finland to Sweden.

DESIGN

A longitudinal study based on the Finnish Twin Cohort Study. Information about migration from Finland to Sweden, duration of stay in Sweden for the migrants, and deaths 1976-1995 was obtained from national registers. Observed numbers of deaths in migrants were compared with expected numbers based on the age standardised mortality experience of the Finnish Twin Cohort. First deaths in migrants and non-migrants of migrant discordant pairs were compared controlling for genetic and early childhood factors.

PARTICIPANTS

Twin pairs of the Finnish Twin Cohort Study where at least one twin had migrated to Sweden (1542 twin pairs).

MAIN RESULTS

Among men, migrants from Finland to Sweden showed an overall similar mortality compared with all subjects of the Finnish Twin Cohort (SMR 1.1; 95% CI 0.9 to 1.4). Mortality from non-violent causes was increased for migrants with at most 20 years in Sweden (SMR 1.9; 95% CI 1.2 to 2.6) and decreased in those with a longer stay (SMR 0.7; 95% CI 0.4 to 0.9). Similar results were obtained concerning first deaths in twin pairs discordant for migration. Among women, migrants had an increased mortality overall (SMR 1.4; 95% CI 1.0 to 1.8), from cardiovascular disease (SMR 1.7; 95% CI 1.0 to 2.7), and from violent causes (SMR 2.5; 95% CI 1.2 to 4.6) compared with all women of the Finnish Twin Cohort. In analyses of migrant discordant pairs only first deaths from cardiovascular disease tended to be more common in the migrants than in non-migrant co-twins.

CONCLUSIONS

Migrants from Finland to Sweden seem to have an overall mortality comparable to that prevailing in Finland suggesting no strong influence on mortality by the migration. Duration of stay seems to be associated with mortality in the migrants, at least in men, with a lower mortality after several years in Sweden.

摘要

研究目的

芬兰的总体死亡率以及主要死因的死亡率高于瑞典,主要体现在男性方面。本研究的目的是分析从芬兰移民到瑞典的人群的死亡率。

设计

一项基于芬兰双胞胎队列研究的纵向研究。从国家登记处获取了有关从芬兰移民到瑞典的信息、移民在瑞典的停留时间以及1976 - 1995年期间的死亡情况。将移民中的观察到的死亡人数与基于芬兰双胞胎队列年龄标准化死亡率经验得出的预期死亡人数进行比较。在控制遗传和儿童早期因素的情况下,比较了移民不一致双胞胎对中移民和非移民的首次死亡情况。

参与者

芬兰双胞胎队列研究中的双胞胎对,其中至少有一个双胞胎移民到了瑞典(1542对双胞胎)。

主要结果

在男性中,从芬兰移民到瑞典的人与芬兰双胞胎队列的所有受试者相比,总体死亡率相似(标准化死亡比[SMR]为1.1;95%置信区间为0.9至1.4)。在瑞典停留至多20年的移民非暴力原因死亡率增加(SMR为1.9;95%置信区间为1.2至2.6),而停留时间较长的移民死亡率降低(SMR为0.7;95%置信区间为0.4至0.9)。在移民不一致的双胞胎对的首次死亡情况方面也得到了类似结果。在女性中,与芬兰双胞胎队列的所有女性相比,移民总体死亡率增加(SMR为1.4;95%置信区间为1.0至1.8),心血管疾病死亡率增加(SMR为1.7;95%置信区间为1.0至2.7),暴力原因死亡率增加(SMR为2.5;95%置信区间为1.2至4.6)。在仅对移民不一致双胞胎对的分析中,只有心血管疾病导致的首次死亡在移民中似乎比非移民的同卵双胞胎更常见。

结论

从芬兰移民到瑞典的人总体死亡率似乎与芬兰普遍存在的死亡率相当,这表明移民对死亡率没有强烈影响。停留时间似乎与移民的死亡率相关,至少在男性中如此,在瑞典居住几年后死亡率较低。

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