van Horrik Tessa M Z X K, Verkerk Eva W, Geerlings Suzanne E, Kool Rudolf B, Laan Bart J
Amsterdam UMC, University of Amsterdam, Department of Internal Medicine-Infectious Diseases, Amsterdam Institute for Infection and Immunity, Amsterdam Public Health, the Netherlands.
Radboud University Medical Center, IQ Health Science Department, PO Box 9101, Nijmegen 6500 HB, the Netherlands.
EClinicalMedicine. 2024 Aug 16;75:102785. doi: 10.1016/j.eclinm.2024.102785. eCollection 2024 Sep.
The use of peripheral intravenous catheters (PIVCs) contributes to healthcare-associated infections. In 2017, we implemented a multifaceted de-implementation strategy that successfully reduced the inappropriate use of catheters in seven hospitals in the Netherlands (RICAT-1 study). Five years later, we investigated the sustainability of this strategy and the contributing factors.
Multicentre mixed-methods study (RICAT-2), consisting of an observational study and interviews in five hospitals in the Netherlands from May 2022 to June 2023. We screened adult patients with PIVCs admitted to internal medicine and non-surgical subspecialty wards. We excluded patients admitted for an elective short stay or terminally ill. Primary endpoint was the percentage of inappropriate PIVCs. We used logistic regression analyses to compare RICAT-2 to the RICAT-1 baseline data. We interviewed 18 healthcare professionals and managers involved in RICAT-1 and/or quality management. We combined thematic inductive analysis and framework analysis.
In RICAT-1 baseline, we included 22.0% (282/1284) inappropriate PIVCs. In RICAT-2, we included 13.8% (154/1113) inappropriate PIVCs (odds ratio 0.76, 95% CI 0.68 to 0.84, p < 0.001). We observed no association between the number of maintained strategy components and the sustained effect. For most hospitals, a small temporary investment in a de-implementation strategy was sufficient to achieve sustained effects. The main facilitator for reducing inappropriate catheters was intrinsic motivation to reduce catheter-associated infections. Main barriers were other priorities, lack of time, and not having a dedicated clinical champion.
Since inappropriate PIVC use was still lower after five years than before the de-implementation strategy, healthcare professionals should be encouraged to adopt this strategy.
This project was funded by The Netherlands Organisation for Health Research and Development (project number: 839205002).
外周静脉导管(PIVC)的使用会导致医疗相关感染。2017年,我们实施了一项多方面的去实施策略,成功减少了荷兰七家医院中导管的不当使用(RICAT - 1研究)。五年后,我们调查了该策略的可持续性及相关影响因素。
多中心混合方法研究(RICAT - 2),包括2022年5月至2023年6月在荷兰五家医院进行的一项观察性研究和访谈。我们筛选了入住内科和非手术专科病房且使用PIVC的成年患者。我们排除了因择期短期住院或身患绝症而入院的患者。主要终点是不当PIVC的百分比。我们使用逻辑回归分析将RICAT - 2与RICAT - 1基线数据进行比较。我们采访了18名参与RICAT - 1和/或质量管理的医疗专业人员和管理人员。我们结合了主题归纳分析和框架分析。
在RICAT - 1基线中,我们纳入了22.0%(282/共1284)的不当PIVC。在RICAT - 2中,我们纳入了13.8%(154/共1113)的不当PIVC(优势比0.76,95%置信区间0.68至0.84,p < 0.001)。我们观察到维持的策略组件数量与持续效果之间无关联。对于大多数医院而言,在去实施策略上进行少量的临时投入就足以实现持续效果。减少不当导管使用的主要促进因素是减少导管相关感染的内在动力。主要障碍是其他优先事项、时间不足以及没有专门的临床倡导者。
由于五年后不当PIVC的使用仍低于去实施策略实施前,应鼓励医疗专业人员采用该策略。
本项目由荷兰卫生研究与发展组织资助(项目编号:839205002)。